The Clinical Profile of Oral Lichen Planus

Authors

  • Syed Murad Ali Shah, Dr. Sardar Begum Dental College Peshawar
  • Muhammad Ilyas, Dr. Sardar Begum Dental College Peshawar
  • Jawad Ahmad Kundi, Dr. Sardar Begum Dental College, Peshawar

DOI:

https://doi.org/10.37762/jgmds.3-01.45

Keywords:

Oral Lichen Planus, Clinical Profile, Oral Mucosa

Abstract

OBJECTIVES
The objective of the study was to determine the clinical profile of oral lichen planus.
METHODOLOGY
This retrospective cohort study was carried from January 2011 to December 2015 at the Department of Oral and Maxillofacial Surgery, Sardar Begum Dental College, Peshawar.A total of 36 with 14 male and 22 female patients having oral lichen planus from were selected. On defined and population-based sample the age selected was ≥ 20 years and divided into four categories i.e..,20-29 years,30-39 years,40-49 years and 50-59 years. The diagnostic criteria proposed by van der Meij et al 23 in 2003 based on the WHO definition of oral lichen planus were used to identify the cases of oral lichen planus.That entire patient’s with incomplete records and aged > 60 years were excluded. The data was analyzed through SPSS 22 at the significance level of p < 0.05 and Chi-square statistics was applied for site and gender association.
RESULTS
The mean age presentation was 39.2 (SD± 15.49) years. The female to male ratio was 1:57:1. The dominant aged group was 30-39 years with n=16 (44.44%).The buccal mucosa was the most common site involved n=28(77.8%).Reticular type of oral lichen planus was the most common form and was present in n=22(61.1%) patients however, bilaterally involved mucosa was commonly seen. Chi-square statistics showed a significant association between bilateral involvement of oral mucosa in oral lichen planus with both male and female (x2= 5.833, p= 0.016).
CONCLUSION
The most common site involved in oral lichen planus was buccal mucosa, most common form was atrophic with female predominance and bilaterally involved oral mucosa was significantly associated with gender.

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References

Sugerman PB, Savage NW, Walsh LJ, Zhao ZZ, Zhou XJ, Khan A, et al. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med 2002;13:350-65 DOI: https://doi.org/10.1177/154411130201300405

Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K. Current controversies in oral lichen planus: Report of an international consensus meeting. Part 1. Viral infections and etiopathogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;100:40-51 DOI: https://doi.org/10.1016/j.tripleo.2004.06.077

Scully C, el-Kom M. Lichen planus: Review and update on pathogenesis. J Oral Pathol 1985;14:431-58 DOI: https://doi.org/10.1111/j.1600-0714.1985.tb00516.x

Steffen C, Dupree ML. Louis-Frédéric Wickham and the Wickham’s striae of lichen planus. Skinmed 2004;3:287-9 DOI: https://doi.org/10.1111/j.1540-9740.2004.02647.x

Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg. 2008; 46(1): 15-21 DOI: https://doi.org/10.1016/j.bjoms.2007.07.199

Andreason JO. Oral lichen planus: A clinical evaluation of 115 cases. Oral Surg Oral Med Oral Pathol. 1968; 25: 31-42 DOI: https://doi.org/10.1016/0030-4220(68)90194-1

Soames JV, Southam JC. Dermatological causes of white patches: Lichen planus. J.V Soames and JC Southam’s Textbook of Oral Pathology. Oxford University Press Pakistan. 2005; 4th ed.:128-130

Bermejo-Fenoll A, Sánchez-Siles M, López-Jornet P, Camacho-Alonso F, Salazar-Sánchez N. A retrospective clinicopathological study of 550 patients with oral lichen planus in south-eastern Spain. J Oral Pathol Med. 2010;39:491–6 DOI: https://doi.org/10.1111/j.1600-0714.2010.00894.x

Chainani-Wu N, Silverman S, Jr, Lozada-Nur F, Mayer P, Watson JJ. Oral lichen planus: Patient profile, disease progression and treatment responses. J Am Dent Assoc. 2001;132:901–9 DOI: https://doi.org/10.14219/jada.archive.2001.0302

Farhi D, Dupin N. Pathophysiology, etiologic factors, and clinical management of oral lichen planus, part I: Facts and controversies. Clin Dermatol. 2010;28:100–8 DOI: https://doi.org/10.1016/j.clindermatol.2009.03.004

Edwards PC, Kelsch R. Oral lichen planus: Clinical presentation and management. J Can Dent Assoc. 2002;68:494–9

Eisen D. The evaluation of cutaneous, genital, scalp, nail, esophageal, and ocular involvement in patients with oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:431–6 DOI: https://doi.org/10.1016/S1079-2104(99)70057-0

Shi P, Liu W, Zhou ZT, He QB, Jiang WW. Podoplanin and ABCG2: Malignant transformation risk markers for oral lichen planus. Cancer Epidemiol Biomarkers Prev. 2010;19:844–9 DOI: https://doi.org/10.1158/1055-9965.EPI-09-0699

Eisen D. The clinical features, malignant potential, and systemic associations of oral lichen planus: A study of 723 patients. J Am Acad Dermatol. 2002;46:207–14 DOI: https://doi.org/10.1067/mjd.2002.120452

Andreasen JO. Oral lichen planus. 1. A clinical evaluation of 115 cases. Oral Surg Oral Med Oral Pathol. 1968;25:31–42. 16. Silverman S, Jr, Gorsky M, Lozada-Nur F. A prospective follow-up study of 570 patients with oral lichen planus: Persistence, remission, and malignant association. Oral Surg Oral Med Oral Pathol.1985;60:30–4. 17. Gandolfo S, Richiardi L, Carrozzo M, Broccoletti R, Carbone M, Pagano M, et al. Risk of oral squamous cell carcinoma in 402 patients with oral lichen planus: A follow-up study in an Italian population. Oral Oncol. 2004;40:77–83. 18. Carbone M, Arduino PG, Carrozzo M, Gandolfo S, Argiolas MR, Bertolusso G, et al. Course of oral lichen planus: A retrospective study of 808 northern Italian patients. Oral Dis. 2009;15:235–43. 19. Murti PR, Daftary DK, Bhonsle RB, Gupta PC, Mehta FS, Pindborg JJ. Malignant potential of oral lichen planus: Observations in 722 patients from India. J Oral Pathol. 1986;15:71–7. September 2016 - March 2017 31

Pakfetrat A, Javadzadeh-Bolouri A, Basir-Shabestari S, Falaki F. Oral Lichen Planus: A retrospective study of 420 Iranian patients. Med Oral Patol Oral Cir Bucal. 2009;14:E315–8

Xue JL, Fan MW, Wang SZ, Chen XM, Li Y, Wang L. A clinical study of 674 patients with oral lichen planus in China. J Oral Pathol Med. 2005;34:467–72 DOI: https://doi.org/10.1111/j.1600-0714.2005.00341.x

van der Meij EH, Schepman KP, van der Waal I. The possible premalignant character of oral lichen planus and oral lichenoid lesions: A prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003; 96: 164-171 DOI: https://doi.org/10.1016/S1079-2104(03)00305-6

Munde AD, Karle RR, Wankhede PK, Shaik SS, Kulkurni M. Demography and clinical profile of Oral Lichen Planus: A retrospective study.Contemp Clin Dent. 2013 Apr;4(2):181-5 DOI: https://doi.org/10.4103/0976-237X.114873

Ingafou M, Leao JC, Porter SR, Scully C. Oral Lichen planus: A retrospective study of 690 British patients. Oral Dis. 2006; 12: 463-468 DOI: https://doi.org/10.1111/j.1601-0825.2005.01221.x

Bermejo-Fenoll A, Sa`nchez-Siles M, Lo`pez-Jornet P, Camacho-Alonso F, Salazar-Sa`nchez N. A retrospective clinicopathological study of 550 patients with oral lichen planus in south-eastern Spain. J Oral Pathol Med. 2010; 39: 491-496 DOI: https://doi.org/10.1111/j.1600-0714.2010.00894.x

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Published

2016-09-01

How to Cite

Shah, S. M. A., Ilyas, M., & Kundi, J. A. (2016). The Clinical Profile of Oral Lichen Planus. Journal of Gandhara Medical and Dental Science, 3(01), 27–31. https://doi.org/10.37762/jgmds.3-01.45

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