Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation

Authors

  • Tania Khattak Frontier Medical College, Abbottabad.
  • Almas Khattak North West School of Medicine, Peshawar
  • Susan Kakakhel North West School of Medicine, Peshawar
  • Anwar Ul Haque North West School of Medicine, Peshawar

DOI:

https://doi.org/10.37762/jgmds.8-3.189

Keywords:

Cholelithiasis, Chronic Cholecystitis, Cholecystectomy, Rokitansky-Aschoff sinuses

Abstract

OBJECTIVES:

The aim of this study was to establish true histopathology proven diagnosis of chronic cholecystitis.

METHODOLOGY:

A cross-sectional study was conducted on 51 post-surgical gallbladders was done to assess their histopathological patterns in a single centered tertiary care hospital. The specimens were studied for chronic cholecystitis, fibrosis, hypertrophy and presence of Rokitansky-Aschoff sinuses. Descriptive analysis was done and associations of the histopathological changes with demographic data of patients were analyzed through Chi-squared test.

RESULTS:

Fifty-one post cholecystectomy samples of gallbladder were analyzed for histopathological changes with 82.4% showing chronic cholecystitis, 84.3% fibrosis, 64.7% congestion, and more than 60% mild or moderate hypertrophy. Moreover, 49% of the specimens showed Rokitansky-Aschoff sinuses. All these changes suggest chronic inflammation.

CONCLUSION:

Chronic cholecystitis, fibrosis, and Rokitansky-Aschoff sinuses are the most common histopathological findings in specimens of patients undergone cholecystectomy for cholelithiasis.

 

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Author Biographies

Tania Khattak, Frontier Medical College, Abbottabad.

Assistant Professor,

Frontier Medical College, Abbottabad.

Almas Khattak, North West School of Medicine, Peshawar

Asst. Prof. North West School of Medicine, Peshawar

Susan Kakakhel, North West School of Medicine, Peshawar

Asst. Prof. North West School of Medicine, Peshawar

Anwar Ul Haque, North West School of Medicine, Peshawar

Prof.

North West School of Medicine, Peshawar

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Published

2021-07-01

How to Cite

Khattak, T., Khattak, A., Kakakhel, S., & Haque, A. U. (2021). Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation. Journal of Gandhara Medical and Dental Science, 8(3), 15–19. https://doi.org/10.37762/jgmds.8-3.189

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