Frequency of Hypertension in Patients with Ischaemic and Haemorrhagic Stroke Presenting at Hayatabad Medical Complex
DOI:
https://doi.org/10.37762/jgmds.13-2.810Keywords:
Ischemic Stroke, Hemorrhagic Stroke, HypertensionAbstract
ABSTRACT
OBJECTIVES
This study aimed to determine the frequency of hypertension and its association with stroke subtype (ischaemic and haemorrhagic) among patients presenting with stroke at Hayatabad Medical Complex.
METHODOLOGY
This cross-sectional study was conducted from June to December 2024 at the Department of Medicine, Hayatabad Medical Complex, Peshawar. All patients presenting with either ischemic or hemorrhagic stroke were included. Data were collected on hypertension status, obesity, ICU admission, and adherence to antihypertensive medication. Descriptive statistics were used to summarize patient characteristics, and associations between stroke subtypes and selected variables were explored.
RESULTS
Among 220 stroke patients, the mean age was 58.35 ± 13.78 years, with a median age of 60 years (IQR: 50–69). The mean BMI was 27.54 ± 5.24 kg/m², and the median length of hospital stay was 4 days (IQR: 2–6). Ischaemic stroke accounted for 69.1% of cases, while 30.9% had haemorrhagic stroke. Hypertension was present in 75% of patients. There was a significant association between hypertension and stroke type (χ² = 30.91, p < 0.001), with hypertensive patients more frequently experiencing ischaemic stroke. In bivariate logistic regression analysis, hypertension, age category, and medication adherence were significantly associated with stroke type. After adjustment in the multivariable logistic regression model, hypertension (AOR = 0.15, p < 0.001), age category (AOR = 0.24, p < 0.001), and medication adherence (AOR = 0.49, p = 0.046) remained significant predictors. The Hosmer–Lemeshow test demonstrates good calibration and adequate fit to the data.
CONCLUSION
Hypertension was highly prevalent among patients with both ischemic and hemorrhagic stroke in this study population, highlighting its importance as a major modifiable risk factor. Strengthening hypertension screening and control programs may help reduce the burden of stroke.
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Toyoda K, Yoshimura S, Nakai M, Koga M, Sasahara Y, Sonoda K, et al. Twenty-year change in severity and outcome of ischaemic and haemorrhagic strokes. JAMA Neurol. 2022;79(1):61-69. https://doi.org/10.1001/jamaneurol.2021.4396 PMID: 34709371
Powers WJ. Acute ischaemic stroke. N Engl J Med. 2020;383(3):252-260. https://doi.org/10.1056/NEJMcp1917030 PMID: 32640133
Montaño A, Hanley DF, Hemphill JC. Hemorrhagic stroke. Handb Clin Neurol. 2021;176:229-248. https://doi.org/10.1016/B978-0-444-64034-5.00016-9 PMID: 33632640
Akinyemi RO, Owolabi MO, Ihara M, Damasceno A, Ogunniyi A, Dotchin C, et al. Stroke, cerebrovascular diseases and vascular cognitive impairment in Africa. Brain Res Bull. 2019;145:97-108. https://doi.org/10.1016/j.brainresbull.2018.10.014 PMID: 30342028
Nasim H, Butt NI, Ashfaq F, Anwar A, Aftab S, Muaaz M. Frequency of modifiable risk factors in ischaemic stroke patients at a tertiary care hospital in Lahore, Pakistan. Pak J Med Res. 2023;62(2):53-58.
Cipolla MJ, Liebeskind DS, Chan SL. The importance of comorbidities in ischaemic stroke: Impact of hypertension on the cerebral circulation. J Cereb Blood Flow Metab. 2018;38(12):2129-2149. https://doi.org/10.1177/0271678X18800589 PMID: 30118333
Cui Q. Modifiable and non-modifiable risk factors in ischaemic stroke: A meta-analysis. Afr Health Sci. 2019;19(2):2121-2129. https://doi.org/10.4314/ahs.v19i2.45 PMID: 31656477
Nindrea RD, Hasanuddin A. Non-modifiable and modifiable factors contributing to recurrent stroke: A systematic review and meta-analysis. Clin Epidemiol Glob Health. 2023;20:101237. https://doi.org/10.1016/j.cegh.2023.101237
Babaeva Z, Uteuliyev Y, Tekebaeva L, Karibaev K. The modified risk factors of ischaemic stroke. J Clin Med Kaz. 2018;4(50):15-20. https://doi.org/10.23950/1812-2892-JCMK-00494
Fatima N, Salman M, Husnain Hashim AA, Sayed TM, Waheed S. Prevalence of newly diagnosed hypertension in stroke patients presented to tertiary care hospitals in Rawalpindi. Pak J Med Health Sci. 2022;16(9):826-828
Woo D, Haverbusch M, Sekar P, Kissela B, Khoury J, Schneider A, et al. Effect of untreated hypertension on hemorrhagic stroke. Stroke. 2004;35(7):1703-1708. https://doi.org/10.1161/01.STR.0000130857.70601.2B PMID: 15155964
Kumar S. Hypertension and hemorrhagic stroke. Hypertens J. 2017;3(2):89-93
Abdu H, Tadese F, Seyoum G. Comparison of ischemic and hemorrhagic stroke in the medical ward of Dessie Referral Hospital, northeast Ethiopia: A retrospective study. Neurol Res Int. 2021;2021:5580456. https://doi.org/10.1155/2021/5580456 PMID: 34367815 PMCID: PMC8342433
Arshi S, Naheed F, Badshah M, Naz F, Fasih-un-Nisa. Hemorrhagic and ischaemic stroke frequency in hypertensive patients presenting with stroke at the Pakistan Institute of Medical Sciences, Islamabad. Prof Med J. 2012;19(3):281-285.
Sherin A, Ul-Haq Z, Fazid S, Shah BH, Khattak MI, Nabi F. Prevalence of stroke in Pakistan: Findings from Khyber Pakhtunkhwa Integrated Population Health Survey (KP-IPHS) 2016-17. Pak J Med Sci. 2020;36(7):1435-1440. https://doi.org/10.12669/pjms.36.7.2325 PMID: 33195604 PMCID: PMC7605225
O'Donnell MJ, Chin SL, Rangarajan S, Xavier D, Liu L, Zhang H, et al. Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE study). Lancet. 2016;388(10046):761-775. https://doi.org/10.1016/S0140-6736(16)30506-2 PMID: 27431356
Feigin VL, Norrving B, Mensah GA. Global burden of stroke. Circ Res. 2017;120(3):439-448. https://doi.org/10.1161/CIRCRESAHA.116.308413 PMID: 28154096
Burnier M, Egan BM. Adherence in hypertension: A review of prevalence, risk factors, impact, and management. Circ Res. 2019;124(7):1124-1140. https://doi.org/10.1161/CIRCRESAHA.118.313220 PMID: 30920917
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Copyright (c) 2026 Muhammad Bilal, Muhammad Ishfaq, Muhammad Usman Khattak, Sadiq Ali Shah, Safi Ullah, Abdul Wahab

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