Left Ventricular Hypertrophy In Ischemic Stroke Patients Single Center Experience
DOI:
https://doi.org/10.37762/jgmds.11-3.600Keywords:
Ischemic Strokes, left ventricular hypertrophy, Transthoracic EchocardiographyAbstract
OBJECTIVES
To ascertain the prevalence of left ventricular hypertrophy in individuals diagnosed with ischemic stroke.
METHODOLOGY
A cross-sectional study was undertaken in the Department of Medicine, Hayatabad Medical Complex, Peshawar, from October 1, 2020, to April 30, 2021, after obtaining ethical approval. The study included 143 individuals who had evidence of ischemic stroke on a CT scan. These patients were assessed for the presence or absence of left ventricular hypertrophy using transthoracic echocardiography.
RESULTS
The average age of the participants in the study was 57 years, with a standard deviation of 7.9 years. The sample consisted of 67.8% males and 32.2% females. The average BMI was calculated to be 25.3 + 3.3kg/m2, and 39.9% of the patients were from urban areas. Left ventricular hypertrophy was observed in 16.8% of patients who had experienced an ischemic stroke, with the greatest occurrence rate of 39.9% found in the age range of 50-60 years. There was no significant correlation observed between hypertension, diabetes, location of residence, age, and smoking.
CONCLUSION
Early and precise identification of the modifiable risk factors during the illness, followed by proper intervention, has the potential to decrease the incidence of debilitating stroke greatly. It is necessary to conduct large-scale population screening studies inside our local community. TTE should be carried out in all acute ischemic stroke patients to optimize the management of these patients.
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Feigin VL, Krishnamurthi RV, Parmar P, Norrving B, Mensah GA, Bennett DA, et al. Update on the Global Burden of Ischemic and Hemorrhagic Stroke in 1990-2013: The GBD 2013 Study. Neuroepidemiol 2015; 45(3):161-76 DOI: https://doi.org/10.1159/000441085
Rajsic S, Gothe H, Borba HH, Sroczynski G, Vujicic J, Toell T. Economic burden of stroke: a systematic review on post-stroke care. European J Health Econ. 2019; 20(1):107-34 DOI: https://doi.org/10.1007/s10198-018-0984-0
Wang H, Wang S, Yi X, Tao Y, Qian H, Jia P et al. Estimate of ischemic stroke prevalence according to a novel 4-tiered classification of left ventricular hypertrophy: insights from the general Chinese population. Ann Med. 2018; 50(6):519-28 DOI: https://doi.org/10.1080/07853890.2018.1500702
Di Tullio MR, Zwas DR, Sacco RL, Sciacca RR, Homma S. Left ventricular mass and geometry and the risk of ischemic stroke. Stroke. 2003;34:2380–2384 DOI: https://doi.org/10.1161/01.STR.0000089680.77236.60
Castilla-Guerra L, Fernandez-Moreno MD, Alvarez-Suero J, Gonzalez A. Echocardiographic assessment of hypertensive left ventricular hypertrophy in patients with acute ischemic stroke or transient ischemic attack. J Stroke Cerebrovasc Dis. 2011 DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2011.03.012
Rodrigo C, Weerasinghe S, Jeevagan V, Rajapakse S, Constantine G. Addressing the relationship between cardiac hypertrophy and ischemic stroke: an observational study. Int Arch Med. 2012; 5(1):32 DOI: https://doi.org/10.1186/1755-7682-5-32
Sasikumar P, Rani PS. Assessment of left ventricular function in ischemic stroke in GDMCH Dharmapuri. Stroke 2017; 4(6):64-70.
Tanne D, Yaari S, Goldbourt U. Risk profile and prediction of long-term ischemic stroke mortality: a 21-year follow-up in the Israeli Ischemic Heart Disease (IIHD) Project. Circulation. 1998; 98:1365–1371 DOI: https://doi.org/10.1161/01.CIR.98.14.1365
Unverzagt FW, McClure LA, Wadley VG, Jenny NS, Go RC, Cushman M, Kissela BM, Kelley BJ, Kennedy R, Moy CS. et al. Vascular risk factors and cognitive impairment in a stroke-free cohort. Neurology. 2011; 77:1729–1736 DOI: https://doi.org/10.1212/WNL.0b013e318236ef23
Bornstein AB, Rao SS, Marwaha K. Left Ventricular Hypertrophy. [Updated 2023 August 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557534
The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischemic stroke International Stroke Trial Collaborative Group. Lancet. May 31 1997;349(9065):1569-81 DOI: https://doi.org/10.1016/S0140-6736(97)04011-7
Shiber JR, Fontane E, Adewale A. Stroke registry: hemorrhagic vs. ischemic strokes. Am J Emerg Med. Mar 2010; 28(3):331-3. DOI: https://doi.org/10.1016/j.ajem.2008.10.026
Bauml MA, Underwood DA. Left ventricular hypertrophy: an overlooked cardiovascular risk factor. Cleve Clin J Med. 2010; 77:381–387 DOI: https://doi.org/10.3949/ccjm.77a.09158
Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. December 14 1995; 333(24):1581-7. DOI: https://doi.org/10.1056/NEJM199512143332401
Hacke W, Kaste M, Bluhmki E, Brozman M, Dávalos A, Guidetti D, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. September 25 2008; 359(13):1317-29 DOI: https://doi.org/10.1056/NEJMoa0804656
Predictors of major vascular events in patients with a transient ischemic attack or non-disabling stroke. The Dutch TIA Trial Study Group. Stroke. 1993; 24:527–531 DOI: https://doi.org/10.1161/01.STR.24.4.527
Khan NI, Naz L, Mushtaq S, Rukh L, Ali S, Hussain Z. Ischemic stroke: prevalence of modifiable risk factors in male and female patients in Pakistan. Pak J Pharm Sci. 2009; 22:62–67
Hayward CS, Kalnins WV, Kelly RP. Gender-related differences in left ventricular chamber function. Cardiovascular research. 2001 Feb 1;49(2):340-50 DOI: https://doi.org/10.1016/S0008-6363(00)00280-7
Kwon HS, Song KH, Yu JM, Kim DS, Shon HS, Ahn KJ, Choi SH, Ko SH, Kim W, Lee KH, Nam-Goong IS. Framingham risk score assessment in subjects with pre-diabetes and diabetes: A cross-sectional study in Korea. Journal of Obesity & Metabolic Syndrome. 2021 Sep 9; 30(3):261 DOI: https://doi.org/10.7570/jomes20137
Kapral MK, Austin PC, Jeyakumar G, Hall R, Chu A, Khan AM, Jin AY, Martin C, Manuel D, Silver FL, Swartz RH, Tu JV. Rural-Urban Differences in Stroke Risk Factors, Incidence, and Mortality in People With and Without Prior Stroke. Circ Cardiovasc Qual Outcomes. 2019 Feb; 12(2):e004973 DOI: https://doi.org/10.1161/CIRCOUTCOMES.118.004973
Del Zoppo GJ, Saver JL, Jauch EC, Adams HP Jr. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke. Aug 2009; 40(8):2945-8 DOI: https://doi.org/10.1161/STROKEAHA.109.192535
Lanni F, Santulli G, Izzo R, Rubattu S, Zanda B, Volpe M, Iaccarino G, Trimarco B. The Pl (A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: increased risk of ischemic stroke in high-risk patients. J Hypertens. 2007; 25:551–556 DOI: https://doi.org/10.1097/HJH.0b013e328013cd67
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