Prevalence of Biliary Dilatation in Patients with Pancreatitis on MDCT and Its Correlation with CT Severity Index
DOI:
https://doi.org/10.37762/jgmds.13-2.807Keywords:
Pancreatitis, Biliary Dilatation, Multidetector Computed Tomography, CT Severity Index, Balthazar ClassificationAbstract
ABSTRACT
OBJECTIVES
This study aimed to determine the prevalence of biliary dilatation in patients with pancreatitis on multidetector computed tomography (MDCT) and to evaluate its association with the CT Severity Index (CTSI).
METHODOLOGY
Analytical cross-sectional study. Department of Radiology, Rehman Medical Institute, Peshawar, from 1st August 2022 to 31st July 2023. A total of 146 adult patients with clinically suspected or confirmed pancreatitis who underwent contrast-enhanced MDCT were included through non-probability consecutive sampling. Patients with prior hepatobiliary surgery, pancreatic or hepatobiliary malignancy, or incomplete imaging were excluded. Biliary dilatation was defined as a common bile duct diameter >7 mm in patients <60 years and >8 mm in those ≥60 years. The CT Severity Index (CTSI) was calculated using the Balthazar grading system. Image interpretation was performed independently by two experienced radiologists, and interobserver agreement was assessed using Cohen’s kappa statistic. The association between biliary dilatation and CTSI categories was analyzed using the Chi-square test for trend. Prevalence estimates were reported with 95% confidence intervals (CI). Statistical analysis was performed using SPSS version 26.0, with p < 0.05 considered significant.
RESULTS
The mean age of patients was 43.68 ± 11.20 years, and 79 (54.1%) were females. Biliary dilatation was observed in 54 patients (37.0%; 95% CI: 29.30-44.9). According to CTSI classification, 47 (32.2%) patients had mild, 45 (30.8%) moderate, and 54 (37.0%) severe pancreatitis. The proportion of biliary dilatation increased with disease severity, occurring in 13 (27.7%) mild, 15 (33.3%) moderate, and 26 (48.1%) severe cases. Although this trend suggested increasing biliary involvement with greater disease severity, the association did not reach statistical significance (p = 0.086). Interobserver agreement for CT interpretation demonstrated substantial reliability (κ = 0.82).
CONCLUSION
Biliary dilatation is a relatively common MDCT finding in patients with pancreatitis and shows an increasing trend with higher CTSI categories. Although the association was not statistically significant, careful CT evaluation of the biliary system may help identify patients who may benefit from further biliary assessment or targeted clinical management.
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Walkowska J, Zielinska N, Tubbs RS, Podgórski M, Dłubek-Ruxer J, Olewnik Ł. Diagnosis and treatment of acute pancreatitis. Diagnostics (Basel). 2022;12(8):1974. https://doi.org/10.3390/diagnostics12081974 PMID: 36011125; PMCID: PMC9409874 DOI: https://doi.org/10.3390/diagnostics12081974
Liao Q, He WH, Li TM, Lai C, Yu L, Xia LY, et al. Evaluation of severity and prognosis of acute pancreatitis by CT severity index and modified CT severity index. Zhonghua Yi Xue Za Zhi. 2022;102(26):2011-2017. PMID: 35801833
Marchegiani G, Barreto SG, Bannone E, Sarr M, Vollmer CM Jr, Connor S, et al. Postpancreatectomy acute pancreatitis (PPAP): Definition and grading from the International Study Group for Pancreatic Surgery (ISGPS). Ann Surg. 2022;275(4):663-672. https://doi.org/10.1097/SLA.0000000000005177 PMID: 35089850. DOI: https://doi.org/10.1097/SLA.0000000000005226
Sun H, Jian S, Peng B, Hou J. Comparison of magnetic resonance imaging and computed tomography in the diagnosis of acute pancreatitis: A systematic review and meta-analysis of diagnostic test accuracy studies. Ann Transl Med. 2022;10(7):410. https://doi.org/10.21037/atm-22-1161 PMID: 35425659; PMCID: PMC8993495 DOI: https://doi.org/10.21037/atm-22-812
Benson M, Goncharov DA, Jain S. Diagnosis and management of acute pancreatitis in pregnancy. Clin Obstet Gynecol. 2023;66(1):237-249. https://doi.org/10.1097/GRF.0000000000000743 PMID: 36640758 DOI: https://doi.org/10.1097/GRF.0000000000000737
Garg PK, Meena D, Babu D, Padhan RK, Dhingra R, Krishna A, et al. Endoscopic versus laparoscopic drainage of pseudocyst and walled-off necrosis following acute pancreatitis: A randomized trial. Surg Endosc. 2020;34(3):1157-1166. https://doi.org/10.1007/s00464-019-06804-1 PMID: 30903255. DOI: https://doi.org/10.1007/s00464-019-06866-z
Zhang Y, Bai L, Wen Y, Ke X, Xie Y, Zhang W, et al. Differential diagnosis of pancreatic cystic masses with quantitative analysis of spectral CT imaging: Initial results. Int J Radiat Res. 2021;19(1):155-165 DOI: https://doi.org/10.29252/ijrr.19.1.155
Colvin SD, Smith EN, Morgan DE, Porter KK. Acute pancreatitis: An update on the revised Atlanta classification. Abdom Radiol (NY). 2020;45(5):1222-1231.https://doi.org/10.1007/s00261-019-02301-0 PMID: 31786769 DOI: https://doi.org/10.1007/s00261-019-02214-w
Mederos MA, Reber HA, Girgis MD. Acute pancreatitis: A review. JAMA. 2021;325(4):382-390.https://doi.org/10.1001/jama.2020.20317 PMID: 33464312 DOI: https://doi.org/10.1001/jama.2020.20317
Ektov VN, Khodorkovsky MA, Skorynin OS, Minakov OE. Atlanta 2012 classification: Terminology and definitions in the diagnosis of acute pancreatitis. J Exp Clin Surg. 2021;14(4):325-333 DOI: https://doi.org/10.18499/2070-478X-2021-14-4-325-333
Lee PJ, Papachristou GI. New insights into acute pancreatitis. Nat Rev Gastroenterol Hepatol. 2019;16(8):479-496.https://doi.org/10.1038/s41575-019-0158-2 PMID: 31160720 DOI: https://doi.org/10.1038/s41575-019-0158-2
Tartari C, Poroes F, Schmidt S, Abler D, Vetterli T, Depeursinge A, et al. MRI and CT radiomics for the diagnosis of acute pancreatitis. Eur J Radiol Open. 2025;14:100636. https://doi.org/10.1016/j.ejro.2025.100636 PMID: 38874229; PMCID: PMC11589772 DOI: https://doi.org/10.1016/j.ejro.2025.100636
Apisarnthanarak P, Boonsri P, Suvannarerg V, Chaiyasoot W, Pongprasobchai S, Apisarnthanarak A. Comparison of CT severity index and modified CT severity index in the clinical severity assessment of acute pancreatitis. J Health Sci Med Res. 2022;40(4):425-435. https://doi.org/10.31584/jhsmr.2022878 DOI: https://doi.org/10.31584/jhsmr.2021854
Hameed M, Hameed S, Harvey C, Moser S, Muthusamy A. Imaging in whole-organ pancreatic transplants and a multimodality review of its complications. Br J Radiol. 2021;94(1122):20200106.https://doi.org/10.1259/bjr.20200106 PMID: 33631118; PMCID: PMC8113232 DOI: https://doi.org/10.1259/bjr.20200106
Agrawal B. Diagnostic value of multidetector computed tomography in evaluation of clinically diagnosed patients of obstructive jaundice. Int J Life Sci Biotechnol Pharma Res. 2024;13:12-18
Khalaf N, El-Serag HB, Abrams HR, Thrift AP. Burden of pancreatic cancer: From epidemiology to practice. Clin Gastroenterol Hepatol. 2021;19(5):876-884. https://doi.org/10.1016/j.cgh.2020.08.065 PMID: 32882383 DOI: https://doi.org/10.1016/j.cgh.2020.02.054
Klein AP. Pancreatic cancer epidemiology: Understanding the role of lifestyle and inherited risk factors. Nat Rev Gastroenterol Hepatol. 2021;18(7):493-502. https://doi.org/10.1038/s41575-021-00457-x PMID: 33927351 DOI: https://doi.org/10.1038/s41575-021-00457-x
Li QY, Luo Y, Chen H, Kong R, Wang YW, Li GQ, et al. Analysis of clinical features and risk factors for severe acute pancreatitis complicated with biliary system diseases. Zhonghua Wai Ke Za Zhi. 2025;63(8):713-720
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Copyright (c) 2026 Ashfaq Ahmad, Ummara Siddique Umer, Ghulam Ghaus, Hira Sayed, Muhammad Hasnat, Mohsin Khan, Hadia Abid

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