Lamotrigine Induced Drug Reaction with Eosinophilia and Systemic Symptoms (Dress) Syndrome, Dysphagia and Steroid Pulse Therapy. A Case Report

Authors

  • Shahida Naz Peshawar Institute of Medical Sciences (PIMS), Peshawar
  • Raza Ullah Hayatabad Medical Complex, Peshawar
  • Haleema Rehman Medical Institute, Peshawar

DOI:

https://doi.org/10.37762/jgmds.10-3.393

Keywords:

Dress Syndrome, Eosinophilia, Drug Reaction, Hypersensitivity Reaction, Exanthema

Abstract

OBJECTIVES

Adverse drug reactions are common, and dermatological manifestation is a common indicator. The potentially lethal "Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome" is one example of severe drug reactions manifesting within weeks after drug intake. It is characterized by "fever, skin rash, lymphadenopathy, eosinophilia and systemic symptoms". We present a case of DRESS syndrome secondary to anticonvulsants lamotrigine associated with dysphagia and responding to steroid pulse therapy.

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Author Biographies

Shahida Naz, Peshawar Institute of Medical Sciences (PIMS), Peshawar

Assistant Professor, Department of Dermatology,
Peshawar Institute of Medical Sciences (PIMS), Peshawar

Raza Ullah, Hayatabad Medical Complex, Peshawar

Assistant Professor, Department of Pulmonology and Critical Care,
Hayatabad Medical Complex, Peshawar

Haleema, Rehman Medical Institute, Peshawar

Trainee Medical Officer,
Rehman Medical Institute, Peshawar

References

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Published

2023-07-01

How to Cite

Naz, S. ., Ullah, R., & Haleema. (2023). Lamotrigine Induced Drug Reaction with Eosinophilia and Systemic Symptoms (Dress) Syndrome, Dysphagia and Steroid Pulse Therapy. A Case Report. Journal of Gandhara Medical and Dental Science, 10(3), 90–92. https://doi.org/10.37762/jgmds.10-3.393

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