ROLE OF PAP SMEAR TEST: FROM SCREENING TO CURE IN TERTIARY CARE HOSPITAL
DOI:
https://doi.org/10.37762/jgmds.9-4.344Keywords:
Cervical Cancer, Pap Smear, Cervical Screening, Precancerous LesionsAbstract
OBJECTIVE
This study aims to assess the Pap smear screening method’s accuracy in detecting precancerous lesions.
METHODOLOGY
After fulfilling the inclusion criteria patients were selected, the patient’s bladder was emptied and put in a dorsal position, and Cusco’s speculum was introduced after lubrication followed by insertion of Ayer’s spatula, applied on the transformational zone, and rotated in 360 degrees. Specimen smeared on glass slides and sent to the laboratory with fulfilled lab pre-requisite form. Patients were requested to follow up with a histopathology report.
RESULTS
Mean age of the patient was 38.111+9.461 years. Among the 77 patients whose samples were taken 15.4% were asymptomatic, 32.1% with vaginal discharge, 17.9% vaginal discharge,17.0% with intermenstrual bleeding and 16.7% were having lower abdominal pain with p-value=0.087. Histopathology reports were interpreted upon follow-up visit among those 1.3% came out to be positive for malignancy, 76.6% negative for malignancy while 22.1% had an inadequate sample.
CONCLUSION
The most common method for screening for cervical cancer is the Pap smear, but its efficacy in detecting early precancerous lesions is very low, possibly due to laboratory error or false technique to a gynecologist of sample technique in our tertiary care hospital. Other screening methods should be used instead of conventional Pap smear.
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Culp MB, Soerjomataram I, Efstathiou JA, Bray F, Jemal A. Recent global patterns in prostate cancer incidence and mortality rates. European urology. 2020 Jan 1;77(1):38-52
Morales-Campos DY, Snipes SA, Villarreal EK, Crocker LC, Guerrero A, Fernandez ME. Cervical cancer, human papillomavirus (HPV), and HPV vaccination: exploring gendered perspectives, knowledge, attitudes, and cultural taboos among Mexican American adults. Ethnicity & health. 2021 Feb 17;26(2):206-24
Daniyal M, Akhtar N, Ahmad S, Fatima U, Akram M, Asif HM. Update knowledge on cervical cancer incidence and prevalence in Asia. Asian Pac J Cancer Prev. 2015; 16: 3617-20
Batool SA, Sajjad S, Malik H. Cervical cancer in Pakistan: A review. J Pak Med Assoc 2017;67(7): 1074-77
Marcus JZ, Cason P, Downs Jr LS, Einstein MH, Flowers L. The ASCCP Cervical Cancer Screening Task Force endorsement and opinion on the American Cancer Society updated cervical cancer screening guidelines. Journal of lower genital tract disease. 2021 Jul 1;25(3):187-91
Stumbar SE, Stevens M, Feld Z. Cervical cancer and its precursors: a preventative approach to screening, diagnosis, and management. Primary Care: Clinics in Office Practice. 2019 Mar 1;46(1):117-34
Rafique S, Abeera A, Ashfaq M, Sameea B, Anjum S, Baber R. The A Clinical Audit of Pap Smear Test for Screening of Cervical Cancer from Private Teaching Hospital of Pakistan. Annals of Punjab Med College (APMC). 2021;15(4):221-4
Vahedpoor Z, Behrashi M, Khamehchian T, Abedzadeh-Kalahroudi M, Moravveji A, Mohmadi-Kartalayi M. Comparison of the diagnostic value of the visual inspection with acetic acid (VIA) and Pap smear in cervical cancer screening. Taiwanese J Obstet and Gynecol. 2019; 58(3):345-8
Bangash A, Hassan SZ, Muhammad G. Causes and Presentation Of Cervical Lymphadenopathy. Journal of Gandhara Medical and Dental Science. 2018 Mar 1;4(2):31-5
Rousset-Jablonski C, Reynaud Q, Nove-Josserand R, Ray-Coquard I, Mekki Y, Golfier F, Durieu I. High proportion of abnormal pap smear tests and cervical dysplasia in women with cystic fibrosis. Euro J Obstet & Gynecol and Reprod Biol. 2018 ;221:40-5
Shaki O, Chakrabarty BK, Nagaraja N. A study on cervical cancer screening in asymptomatic women using Papanicolaou smear in a tertiary care hospital in an urban area of Mumbai, India. J fami med prim care. 2018 ;7(4):652
Khan MS, Raja FY, Ishfaq G, Tahir F, Subhan F, Kazi BM, Karamat KA. Pap smear screening for pre-cancerous conditions of the cervical cancer. Pak J Med Res. 2005;44(3):111-3
Hashmi AA, Naz S, Ahmed O, Yaqeen SR, Irfan M, Asif MG, Kamal A, Faridi N. Comparison of Liquid-Based Cytology and Conventional Papanicolaou Smear for Cervical Cancer Screening: An Experience From Pakistan. Cureu. 2020 ;12(12)
Singhal A, Raina RK, Verma S, Verma A. Predictive accuracy of cervical cytology and colposcopy in diagnosing premalignant and malignant cervical lesions: A hospital-based study from the sub-Himalayan region of Indian subcontinent. CHRISMED Journal of Health and Research. 2019 Jan 1;6(1):39
Rezende MT, Bianchi AGC, Carneiro CM. Cervical cancer: Automation of Pap test screening. Diagn Cytopathol. 2021 ;49(4):559-574
Sachan PL, Singh M, Patel ML, Sachan R. A Study on Cervical Cancer Screening Using Pap Smear Test and Clinical Correlation. Asia Pac J Oncol Nurs. 2018 ;5(3):337-341
Sharif YH. Clinical correlation of CC screening using Pap smear test. Journal of Population Therapeutics and Clinical Pharmacology. 2022 Mar 15;29(01)
Rozendaal L, Walboomers JM, Van Der Linden JC, Voorhorst FJ, Kenemans P, Helmerhosrt TJ, Van Ballegooijen M, Meijer CJ. PCR‐based high‐risk HPV test in cervical cancer screening gives objective risk assessment of women with cytomorphologically normal cervical smears. International journal of cancer. 1996 Dec 11;68(6):766-9
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