Anemia a Contributory Factor Affecting Quality of Life in Type 2 Diabete1s Mellitus Patients
DOI:
https://doi.org/10.37762/jgmds.9-3.297Keywords:
Diabetes mellitus, Anemia, Mean corpuscular volume, Mean corpuscular hemoglobinAbstract
OBJECTIVES:
The study aimed to determine the prevalence of anemia in type 2 diabetes mellitus patients and its effects on the quality of life in diabetic patients.
METHODOLOGY:
A cross-sectional study was conducted at the Department of Pathology, Government Naseer Ullah Khan Babar Memorial Hospital, Peshawar, Pakistan. All diabetic patients admitted to the medical ward were included in this study, and their blood samples were obtained in heparinised and EthyleneDiamineTetracetic Acid (EDTA) tubes by aseptic technique after informed consent. All samples were assessed for sugar levels and complete blood count.
RESULTS:
118 diabetic patients were enrolled in this study, 66% of patients were females, and 34% were males. Female patients in age groups 1, 2 and 3 were more than males, and in age group 4, all patients were male. Anemia was found in about 79% of females and 21% of male patients.
CONCLUSION:
Albuminuria and renal insufficiency are important factors in understanding and investigations of anemia. Diabetic patients must be screened for anemia and treated accordingly to improve the quality of life in such patients and reduce morbidity and mortality rate.
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Taderegew MM, Gebremariam T, Tareke AA, Woldeamanuel GG. Anemia and its associated factors among type 2 diabetes mellitus patients attending Debre Berhan Referral Hospital, North-East Ethiopia: A cross-sectional study. J Blood Med [Internet]. 2020 [cited 2022 Apr 18];11:47–58. DOI: https://doi.org/10.2147/JBM.S243234
Pathak J, Vadodariya V, Jhala A, Bhojwani D, Brahmbhatt N. Anemia in type 2 diabetes mellitus in absence of renal insufficiency. Int J Contemp Med Res [IJCMR] [Internet]. 2019 [cited 2022 Apr 18];6(11) DOI: https://doi.org/10.21276/ijcmr.2019.6.11.26
El-Kebbi IM, Bidikian NH, Hneiny L, Nasrallah MP. Epidemiology of type 2 diabetes in the Middle East and North Africa: Challenges and call for action. World J Diabetes [Internet]. 2021;12(9):1401–25. Available from: http://dx.doi.org/10.4239/wjd.v12.i9.1401 DOI: https://doi.org/10.4239/wjd.v12.i9.1401
S. HK, S. V. S, K. P. Haematological profile of diabetes and non-diabetes patients in rural tertiary centre. Int J Adv Med [Internet]. 2017;4(5):1271 DOI: https://doi.org/10.18203/2349-3933.ijam20174111
Chadt A, Al-Hasani H. Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease. Pflugers Arch [Internet]. 2020;472(9):1273–98 DOI: https://doi.org/10.1007/s00424-020-02417-x
Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med [Internet]. 2019;25(12):1822–32 DOI: https://doi.org/10.1038/s41591-019-0675-0
Tsalamandris S, Antonopoulos AS, Oikonomou E, Papamikroulis G-A, Vogiatzi G, Papaioannou S, et al. The role of inflammation in diabetes: Current concepts and future perspectives. Eur Cardiol [Internet]. 2019;14(1):50–9 DOI: https://doi.org/10.15420/ecr.2018.33.1
Sindhughosa DA, Pranamartha AAGMK. The involvement of proinflammatory cytokines in diabetic nephropathy: Focus on interleukin 1 (IL-1), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-α) signaling mechanism. Bali Med J [Internet]. 2017;6(1):44 DOI: https://doi.org/10.15562/bmj.v6i1.299
George C, Matsha TE, Korf M, Zemlin AE, Erasmus RT, Kengne AP. The agreement between fasting glucose and markers of chronic glycaemic exposure in individuals with and without chronic kidney disease: a cross-sectional study. BMC Nephrol [Internet]. 2020;21(1):32 DOI: https://doi.org/10.1186/s12882-020-1697-z
Hasan M, Sutradhar I, Gupta RD, Sarker M. Prevalence of chronic kidney disease in South Asia: a systematic review. BMC Nephrol [Internet]. 2018;19(1):291 DOI: https://doi.org/10.1186/s12882-018-1072-5
Begum S, Latunde-Dada GO. Anemia of inflammation with an emphasis on chronic kidney disease. Nutrients [Internet]. 2019;11(10):2424 DOI: https://doi.org/10.3390/nu11102424
Gafter-Gvili A, Schechter A, Rozen-Zvi B. Iron deficiency anemia in chronic kidney disease. Acta Haematol [Internet]. 2019;142(1):44–50 DOI: https://doi.org/10.1159/000496492
Kruk ME, Gage AD, Arsenault C, Jordan K, Leslie HH, Roder-DeWan S, et al. High-quality health systems in the Sustainable Development Goals era: time for a revolution. Lancet Glob Health [Internet]. 2018;6(11):e1196–252 DOI: https://doi.org/10.1016/S2214-109X(18)30386-3
Awofisoye OI, Adeleye JO, Olaniyi JA, Esan A. Prevalence and correlates of anemia in type 2 diabetes mellitus: a study of a Nigerian outpatient diabetic population. Sahel Medical Journal. 2019;22(2)
Bekele A, Teji Roba K, Egata G, Gebremichael B. Anemia and associated factors among type-2 diabetes mellitus patients attending public hospitals in Harari Region, Eastern Ethiopia. PLoS One [Internet]. 2019;14(12):e0225725. Available from: http://dx.doi.org/10.1371/journal.pone.0225725 DOI: https://doi.org/10.1371/journal.pone.0225725
Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al. Pathophysiology of type 2 Diabetes Mellitus. Int J Mol Sci [Internet]. 2020;21(17):6275 DOI: https://doi.org/10.3390/ijms21176275
Katwal PC, Jirjees S, Htun ZM, Aldawudi I, Khan S. The effect of anemia and the goal of optimal HbA1c control in diabetes and non-diabetes. Cureus [Internet]. 2020;12(6):e8431 DOI: https://doi.org/10.7759/cureus.8431
Ndako JA, Dojumo VT, Akinwumi JA, Fajobi VO, Owolabi AO, Olatinsu O. Changes in some haematological parameters in typhoid fever patients attending Landmark University Medical Center, Omuaran-Nigeria. Heliyon [Internet]. 2020;6(5):e04002 DOI: https://doi.org/10.1016/j.heliyon.2020.e04002
Yilmaz G, Shaikh H. Normochromic Normocytic Anemia. InStatPearls [Internet]. StatPearls Publishing; 2021
Idris I, Tohid H, Muhammad NA, A Rashid MR, Mohd Ahad A, Ali N, et al. Anemia among primary care patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD): a multicentred cross-sectional study. BMJ Open [Internet]. 2018;8(12):e025125. DOI: https://doi.org/10.1136/bmjopen-2018-025125
Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, et al. IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract [Internet]. 2018;138:271–81 DOI: https://doi.org/10.1016/j.diabres.2018.02.023
Gupta A, Gupta S, Gupta V, Gupta V. Evaluation of incidence of anemia in type 2 diabetic patients with normal renal function. Indian J Pathol Microbiol. 2017;4(1):132–4
Bharathi K. Study of hematological profile and its significance in type 2 diabetes mellitus patients. J Diagn Pathol Oncol. 2016;1:14–7
Wang Y, Wei R-B, Su T-Y, Huang M-J, Li P, Chen X-M. Clinical and pathological factors of renal anemia in patients with IgA nephropathy in Chinese adults: a cross-sectional study. BMJ Open [Internet]. 2019;9(1):e023479 DOI: https://doi.org/10.1136/bmjopen-2018-023479
Aljohani AH, Alrubyyi MA, Alharbi AB. The relation between diabetes type II and anemia. Egypt J Hosp Med [Internet]. 2018;70(4):526–31 DOI: https://doi.org/10.12816/0043795
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