P53 Protein Expression in Epithelial Lining of Odontogenic Cysts: An Immunohistochemical Descriptive Case Study

Authors

  • Aqib Sohail Lahore Medical & Dental College
  • Aneela Amjad Sharif Medical & Dental College. Lahore
  • Nighat Zahid Lahore Medical & Dental College
  • Asad Aizaz Chatha CMH, Lahore Medical College National University of Medical Sciences.
  • Nauman Rauf Khan Sharif Medical and Dental College, Lahore.
  • Aamer Iqbal SIMS, Services Hospital, Lahore
  • Bilal Yusuf THQ Kasur

DOI:

https://doi.org/10.37762/jgmds.8-3.192

Keywords:

P53, Odontogenic Cysts, Dentigerous Cysts, Radicular Cysts, Odontogenic Keratocysts

Abstract

OBJECTIVES:

The current study was conducted to analyze immunohistochemical appearance of P53 protein in odontogenic cysts.

METHODOLOGY:

Thirty paraffin blocks of confirmed case were prepared to investigate the immunohistochemical appearance of P53 protein.

RESULTS:

Sixteen out of thirty odontogenic cysts (53.3%) showed P53, four out of ten dentigerous cyst (40%) had P53, twelve out of fifteen odontogenic keratocysts (80%) expressed P53 while none of the five radicular cysts (0%) showed P53 protein.

CONCLUSION:

Reclassification of OKC as keratocystic odontogenic tumor was supported by the present study and its findings.

 

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Author Biographies

Aqib Sohail, Lahore Medical & Dental College

Principal, Head Department of OMFS,

Lahore Medical and Dental College, Lahore

Aneela Amjad, Sharif Medical & Dental College. Lahore

Associate Professor & HOD Oral Medicine,

Sharif Medical and Dental College, Lahore

Nighat Zahid, Lahore Medical & Dental College

Associate Professor of Oral and Maxillofacial Surgery,

Lahore Medical and Dental College

Asad Aizaz Chatha, CMH, Lahore Medical College National University of Medical Sciences.

Associate Professor of Oral and Maxillofacial Surgery, Institute of Dentistry, CMH,

Lahore Medical College National University of Medical Sciences.

Nauman Rauf Khan, Sharif Medical and Dental College, Lahore.

Principal, Department of Oral Pathology,

Sharif Medical and Dental College, Lahore.

Aamer Iqbal, SIMS, Services Hospital, Lahore

Associate Professor of Oral and Maxillofacial Surgery,

SIMS, Services Hospital, Lahore

Bilal Yusuf, THQ Kasur

Dental Surgeon,

THQ Kasur

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Published

2021-07-01

How to Cite

Sohail, A., Amjad, A., Zahid, N., Chatha, A. A., Khan, N. R., Iqbal, A., & Yusuf, B. (2021). P53 Protein Expression in Epithelial Lining of Odontogenic Cysts: An Immunohistochemical Descriptive Case Study. Journal of Gandhara Medical and Dental Science, 8(3), 29–34. https://doi.org/10.37762/jgmds.8-3.192

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