Depressive Illness among Chronic Liver Disease Patients: A Cross-Sectional Study

Authors

  • Aliena Badshah Khyber Teaching Hospital, Peshawar
  • Qaisar Ali Khan
  • Taimoor Khan Khyber Teaching Hospital Peshawar
  • Arooba Khan Khyber Teaching Hospital Peshawar
  • Amjad Shehzad Khyber Teaching Hospital Peshawar

DOI:

https://doi.org/10.37762/jgmds.11-3.591

Keywords:

chronic liver disease, major depressive disorder, prevalence, age, income, education, comorbidities, depression severity, targeted interventions.

Abstract

OBJECTIVES

This study investigated the association between chronic liver disease and major depressive disorder (MDD) in Pakistani adults. The prevalence of MDD among chronically ill patients admitted to a medical unit was examined, focusing on the impact of age, income, education level, and comorbidities on depression severity.

METHODOLOGY

A descriptive cross-sectional survey was conducted over two months at the Khyber Teaching Hospital in Peshawar. A total of 410 patients with chronic liver disease were included. Depression severity was assessed using the Patient Health Questionnaire-9 (PHQ-9). Data analysis was performed using SPSS version 25, utilizing statistical tests such as Pearson correlation, ANOVA. and chi-square.

RESULTS

The study investigated depression severity among 410 patients with chronic liver disease, focusing on demographic characteristics and comorbidities. The mean age of participants was 54.244 years, with a moderate level of depressive symptoms indicated by a mean PHQ-9 score of 10. Income showed a weak but significant negative correlation with depression severity (-0.138, p = 0.005), while age did not show a significant correlation (-0.053, p = 0.288).

CONCLUSION

This study enhances the understanding of the intricate relationship between chronic liver disease and major depressive disorder (MDD). The results indicate that income level, education level, and the presence of comorbidities significantly influence the manifestation of depression in this population. Healthcare professionals can leverage these insights to identify high-risk patients and tailor interventions to enhance mental well-being and treatment outcomes for individuals with chronic liver disease.

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Author Biographies

Aliena Badshah, Khyber Teaching Hospital, Peshawar

Department of Medicine,
Khyber Teaching Hospital, Peshawar

Qaisar Ali Khan

Trainee Medical officer,
Department of Medicine,
Khyber Teaching Hospital, Peshawar

Taimoor Khan, Khyber Teaching Hospital Peshawar

Trainee Medical officer,
Department of Medicine,
Khyber Teaching Hospital Peshawar

Arooba Khan, Khyber Teaching Hospital Peshawar

Trainee Medical officer,
Department of Medicine,
Khyber Teaching Hospital Peshawar

Amjad Shehzad, Khyber Teaching Hospital Peshawar

Registrar,
Medical ICU,
Khyber Teaching Hospital Peshawar

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Published

2024-06-30

How to Cite

Badshah, A., Khan, Q. A. ., Khan, T. ., Khan, A. ., & Shehzad, A. . (2024). Depressive Illness among Chronic Liver Disease Patients: A Cross-Sectional Study. Journal of Gandhara Medical and Dental Science, 11(3), 3–8. https://doi.org/10.37762/jgmds.11-3.591

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