Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation
DOI:
https://doi.org/10.37762/jgmds.8-3.189Keywords:
Cholelithiasis, Chronic Cholecystitis, Cholecystectomy, Rokitansky-Aschoff sinusesAbstract
OBJECTIVES:
The aim of this study was to establish true histopathology proven diagnosis of chronic cholecystitis.
METHODOLOGY:
A cross-sectional study was conducted on 51 post-surgical gallbladders was done to assess their histopathological patterns in a single centered tertiary care hospital. The specimens were studied for chronic cholecystitis, fibrosis, hypertrophy and presence of Rokitansky-Aschoff sinuses. Descriptive analysis was done and associations of the histopathological changes with demographic data of patients were analyzed through Chi-squared test.
RESULTS:
Fifty-one post cholecystectomy samples of gallbladder were analyzed for histopathological changes with 82.4% showing chronic cholecystitis, 84.3% fibrosis, 64.7% congestion, and more than 60% mild or moderate hypertrophy. Moreover, 49% of the specimens showed Rokitansky-Aschoff sinuses. All these changes suggest chronic inflammation.
CONCLUSION:
Chronic cholecystitis, fibrosis, and Rokitansky-Aschoff sinuses are the most common histopathological findings in specimens of patients undergone cholecystectomy for cholelithiasis.
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Copyright (c) 2021 Tania Khattak, Almas Khattak, Susan Kakakhel, Anwar Ul Haque
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