A Case Report Highlighting Uncommon Histopathological Finding of Papillary Thyroid Cancer within a Thyroglossal Duct Cyst

Authors

  • Momina Zeb Pakistan Institute of Medical Sciences Islamabad

DOI:

https://doi.org/10.37762/jgmds.11-1.566

Keywords:

Thyroglossal Duct Cyst, Midline Neck Mass, Thyroid Disease

Abstract

This study discusses a case involving a 30-year-old male presented in ENT OPD with complaints of painless swelling in front of his neck. Papillary thyroid carcinoma originating from a thyroglossal duct cyst is an infrequent and atypical form of cancer. Typically, it remains undetected until surgical intervention and the optimal approach to its management is a subject of ongoing debate. Here, we present the case of a 30-year-old male who initially presented with a thyroglossal duct cyst but was subsequently diagnosed with papillary thyroid carcinoma. This case report focuses on suspecting having a Thyroglossal duct cyst, presented with painless swelling in front of the neck at the level of the hyoid bone. The mass moved when the tongue protruded but did not move when the patient swallowed. It exhibited a soft consistency during palpation, was not tender, movable, non-compressible, non-reducible, lacked fluctuation, and did not expand on the valsula while showing no changes in overlying skin temperature. TGD carcinoma can sometimes go undetected because it is a rare condition. When dealing with rapidly expanding neck masses in the midline, it's essential to conduct appropriate examinations, including neck imaging and fine-needle aspiration cytology. While the Sistrunk procedure is adequate for squamous carcinoma, differentiated thyroid carcinoma typically necessitates total thyroidectomy as the recommended course of action.

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Author Biography

Momina Zeb, Pakistan Institute of Medical Sciences Islamabad

Postgraduate Resident,
Department of Ent,
Pakistan Institute of Medical Sciences Islamabad

References

Zizic M, Faquin W, Stephen AE, Kamani D, Nehme R, Slough CM et al. Upper neck papillary thyroid cancer (UPTC): a new proposed term for the composite of thyroglossal duct cyst‐associated papillary thyroid cancer, pyramidal lobe papillary thyroid cancer, and Delphian node papillary thyroid cancer metastasis. Laryngoscope. 2016 Jul;126(7):1709-14

Sturniolo G, Vermiglio F, Moleti M. Thyroid cancer in lingual thyroid and thyroglossal duct cyst. Endocrinol Diabetes Nutr. 2017 Jan 1;64(1):40-3

Sun Z, Guo X, Zang M, Wang P, Xue S, Chen G. Long non‐coding RNA LINC00152 promotes cell growth and invasion of papillary thyroid carcinoma by regulating the miR‐497/BDNF axis. J Cell Physiol. 2019 Feb;234(2):1336-45

Agha RA, Franchi T, Sohrabi C, Mathew G, Kerwan A, Thoma A et al. The SCARE 2020 guideline: updating consensus surgical Case Report (SCARE) guidelines. Int J Surg. 2020 Dec 1;84:226-30

Patigaroo SA, Dar NH, Jallu AS, Ahmad R. Thyroglossal duct cysts: A clinicosurgical experience. Indian J Otolaryngol Head Neck Surg. 2017 Mar;69(1):102-7

Van Beck J, Khaja SF. Thyroglossal Duct Cyst Carcinoma in a Young Female: case report and review of literature. Case Rep Otolaryngol. 2019 Jul 31;2019:4069375

Rayess HM, Monk I, Svider PF, Gupta A, Raza SN, Lin HS. Thyroglossal duct cyst carcinoma: a systematic review of clinical features and outcomes. Otolaryngol Head Neck Surg. 2017 May;156(5):794-802

Thompson LDR, Herrera HB, Lau SK. Thyroglossal duct cyst carcinomas: a clinicopathologic series of 22 cases with staging recommendations. Head Neck Pathol. 2017 Jun;11(2):175-85

Lancini D, Lombardi D, Piazza C. Evidence and controversies in management of thyroglossal duct cyst carcinoma. Curr Opin Otolaryngol Head Neck Surg. 2021 Apr;29(2):113-9

Bakkar S, Biricotti M, Stefanini G, Ambrosini CE, Materazzi G, Miccoli P. The extent of surgery in thyroglossal cyst carcinoma. Langenbecks Arch Surg. 2017 Aug;402(5):799-804

Verma R, Patro SK, Damodharan N, Sood A, Bal A. Papillary carcinoma thyroid in a thyroglossal cyst: A management dilemma. Acta Oto Laryngol Case Rep. 2017 Jan 1;2(1):5-10

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Published

2023-12-31

How to Cite

Zeb, M. (2023). A Case Report Highlighting Uncommon Histopathological Finding of Papillary Thyroid Cancer within a Thyroglossal Duct Cyst. Journal of Gandhara Medical and Dental Science, 11(1), 74–76. https://doi.org/10.37762/jgmds.11-1.566