The Effect of Pyeloplasty on Renal Cortical Thickness in the Pediatric Population with Ureteropelvic Junction Obstruction
DOI:
https://doi.org/10.37762/jgmds.10-3.481Keywords:
Pyeloplasty, ureteropelvic junction obstruction, renal cortical thicknessAbstract
OBJECTIVES
To determine the effect of pyeloplasty on renal cortical thickness in the pediatric population with ureteropelvic junction obstruction (UPJO).
METHODOLOGY
This retrospective study examined the renal cortical thickness in 100 pediatric patients diagnosed with ureteropelvic junction obstruction (UPJO). The study employed a non-probability consecutive sampling technique to select participants. Inclusion criteria encompassed children below five years of age, of both genders, with Pakistani nationality, and availability of both pre-and post-operative ultrasound data. Cases presenting with ureterovesical junction obstruction or vesicoureteral reflux were excluded from the analysis. Data collection involved gathering information on age, gender, and cortical thickness, with renal cortical thickness assessed through ultrasonography. A paired t-test was employed to compare the renal cortical thickness between the preoperative assessment and the 3-month follow-up.
RESULTS
The females were 40(40%) and males were 60(60%). The mean age was 33.51±22.91months. The mean cortical thickness before pyeloplasty was 5.23±0.93mm and 8.25 ± 2.34mm after pyeloplasty. The renal cortical thickness in both genders significantly increased to 3mm (p<0.001). The cortical thickness before pyeloplasty was 5.23±0.93mm, and after was 8.25±2.34mm.
CONCLUSION
Renal cortical thickness can be improved after pyeloplasty in patients with ureteropelvic junction obstruction.
Downloads
Metrics
References
Arena S, Chimenz R, Antonelli E, Peri F, Romeo P, Impellizzeri P, et al. A long-term follow-up in conservative management of unilateral ureteropelvic junction obstruction with poor drainage and good renal function. Eur J Pediatr. 2018;177(12):1761-5 DOI: https://doi.org/10.1007/s00431-018-3239-2
Tipton T, Edwards K, Simpson K, Prasad M, Stec A. Pathologic specimens at time of pyeloplasty: frequency and practice patterns. Urology. 2018;122:158–61 DOI: https://doi.org/10.1016/j.urology.2018.08.036
Vemulakonda VM. Ureteropelvic junction obstruction: diagnosis and management. Curr Opin Pediatr. 2021;33(2):227-34 DOI: https://doi.org/10.1097/MOP.0000000000000994
Li B, McGrath M, Farrokhyar F, Braga LH. Ultrasound-Based Scoring System for Indication of Pyeloplasty in Patients With UPJO-Like Hydronephrosis. Front Pediatr. 2020;8:353 DOI: https://doi.org/10.3389/fped.2020.00353
Haq A, Khan I. Tubeless and stentless pyeloplasty. J Pak Med Assoc 2003;17:124–7
Rabani SM, Mousavizadeh A. The dilemma of ureterovesical junction obstruction. Nephro-Urology Monthly. 2017;9(5):34-41 DOI: https://doi.org/10.5812/numonthly.57201
Liu X, Huang C, Guo Y, Yue Y, Hong J. Comparison of DJ stented, external stented and stent-less procedures for pediatric pyeloplasty: a network meta-analysis. Int J Surg. 2019;68:126–133 DOI: https://doi.org/10.1016/j.ijsu.2019.07.001
Song SH, Park S, Chae SY, Moon DH, Park S, Kim KS. Predictors of Renal Functional Improvement After Pyeloplasty in Ureteropelvic Junction Obstruction: clinical Value of Visually Assessed Renal Tissue Tracer Transit in 99mTc-mercaptoacetyltriglycine Renography. Urology. 2017;108:149–154 DOI: https://doi.org/10.1016/j.urology.2017.05.044
Gnech M, Berrettini A, Lopes R, Moscardi P, Esposito C, Zucchetta P, et al. Pyeloplasty vs. nephrectomy for ureteropelvic junction obstruction in poorly functioning kidneys (differential renal function< 20%): a multicentric study. J Pediatr Urol. 2019;15(5):553. e1-. e8 DOI: https://doi.org/10.1016/j.jpurol.2019.05.032
Goetz G, Klora M, Zeidler J, et al. Surgery for pediatric ureteropelvic junction obstruction comparison of outcomes in relation to surgical technique and operating discipline in Germany. Eur J Pediatr Surg. 2019;29:33–38. DOI: https://doi.org/10.1055/s-0038-1668149
Harraz AH, Helmy T, Taha DE. Changes in differential renal function after pyeloplasty in children. J Urol. 2013;190:1468–73 DOI: https://doi.org/10.1016/j.juro.2013.01.004
Harraz AM, Taha DE, Shalaby I, Hafez AT. Evaluation of factors predicting recoverability of renal function after pyeloplasty in adults. Urol Int. 2014;93(4):403–5. DOI: https://doi.org/10.1159/000357625
Imam MS, Al Farooq MA, Sarwar MKA, Chowdhury TK, Khastagir R, Habib MG, et al. A comparison between short-and long-term DJ stent in Anderson–Hynes pyeloplasty for pelvi-ureteric junction obstruction. Pediatr Surg Int. 2020;36:1363-70 DOI: https://doi.org/10.1007/s00383-020-04734-9
Abdelaziz A, Shaker H, Aly H, Aldaqados H, Hussein E. Early outcome of pediatric pyeloplasty in kidneys with split renal function less than 10%: A prospective study of 25 cases. African J Urol. 2018;24(4):324-30 DOI: https://doi.org/10.1016/j.afju.2018.08.003
Ibrahim Selmy G, Mohamed Salih E-S, Salah El-Din Zykri M, Abd El-Maksoud AE-K. outcome of pediatric pyeloplasty in renal units with split renal function less than 20%. Al-Azhar Med J. 2019;48(4):489-500. DOI: https://doi.org/10.21608/amj.2019.64955
Brennan S, Watson D, Schneider M, Rudd D, Kandasamy Y. Can measurement of the foetal renal parenchymal thickness with ultrasound be used as an indirect measure of nephron number? J Dev Orig Health Dis. 2021;12(2):184–192
Huang WY, Peters CA, Zurakowski D, et al. Renal biopsy in congenital ureteropelvic junction obstruction: evidence for parenchymal maldevelopment. Kidney Int. 2006;69(1):137–43 DOI: https://doi.org/10.1038/sj.ki.5000004
Li Y, He Y, Zhang W, Song H, Wang T. Factors predicting improvement of differential renal function after pyeloplasty in children of ureteropelvic junction obstruction. J Pediatr Urol. 2022;20:80-4 DOI: https://doi.org/10.1016/j.jpurol.2022.06.017
Chalieopanyarwong V, Attawettayanon W. Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction. Res Rep Urol. 2021;13:699 DOI: https://doi.org/10.2147/RRU.S324786
Brennan S, Watson D, Schneider M, Rudd D, Kandasamy Y. Can measurement of the foetal renal parenchymal thickness with ultrasound be used as an indirect measure of nephron number? J Dev Orig Health Dis. 2021;12(2):184–92 DOI: https://doi.org/10.1017/S204017442000015X
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Asif Khan, Muhammad Rashid Ullah , Nizamuddin, Syed Mumtaz Ali, Fazli Elahi
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.