Systemic Comorbidities in Patients with Primary Fascial Space Infections of Odontogenic Orogin: Experience of a Tertiary Care Center
DOI:
https://doi.org/10.37762/jgmds.10-3.418Keywords:
Immunocompromised, Systemic comorbidities, fascial space infections, Odontogenic InfectionsAbstract
OBJECTIVES
To assess systemic immune-compromised comorbidities in patients presenting with odontogenic infections that extend to fascial spaces. This study was designed to investigate the incidence of immune-compromising systemic comorbidities among patient presenting with odontogenic infections.
METHODOLOGY
This cross-sectional study was performed at the Department of Maxillofacial Surgery, Hayatabad Medical Complex (HMC) Peshawar from October 2018 through April 2019. However, patients older than 10 years of age, presenting with fascial space infections other than odontogenic cause, secondary fascial space infections and patients with multiple organ failure were excluded. The odontogenic infections were categorized according to their anatomical location. The prevalence of comorbidities was also assessed.
RESULTS
A total of 145 patients were included, where the male to female ratio was 3.8:1, mean age ~ 56 ± 14.74 years (range: 12-80 years) and mean duration of the odontogenic infections was 5± 1.2 days. The submandibular space was the most frequent site involved in odontogenic infections with a frequency of 60 (41.4%), followed by buccal space with 44 (30.3%) patients & canine space with 31 (21.4%) patients. Of the 79 patients with comorbidities out of total 145 patients, diabetes mellitus was recorded in 60 patients. Other comorbidities included hypertension, renal and hepatic impairment.
CONCLUSION
Diabetes mellitus was the most common immune compromising comorbidity presented in patients with odontogenic infections extending in fascial spaces. Assessment of diabetes in routine dental practice is emphasized to avoid exacerbation of the odontogenic infections.
Downloads
Metrics
References
Heim N, Warwas FB, Wiedemeyer V, Wilms CT, Reich RH, Martini M. The role of immediate versus secondary removal of the odontogenic focus in treatment of deep head and neck space infections. A retrospective analysis of 248 patients. Clin Oral Investig. 2019;23(7):2921–7 DOI: https://doi.org/10.1007/s00784-018-02796-7
Rohani B. Oral manifestations in patients with diabetes mellitus. World J Diabetes. 2019;10(9):486–9 DOI: https://doi.org/10.4239/wjd.v10.i9.485
Nazir MA, Alghamdi L, Alkadi M, Albeajan N, Alrashoudi L, Alhussan M. The burden of diabetes, its oral complications and their prevention and management. Maced J Med Sci. 2018;6(8):1545–53 DOI: https://doi.org/10.3889/oamjms.2018.294
Rocha FS, Batista JD, Silva CJ, Júnior RB, Raposo LH. Considerations for the Spread of Odontogenic Infections - Diagnosis and Treatment. InA Textbook of Advanced Oral and Maxillofacial Surgery Volume 2 2015 Apr 22. IntechOpen DOI: https://doi.org/10.5772/59161
Mulholland C, Champion F, Yoon K. The Effect of Immune-compromising Systemic Comorbidities on Outcome Measures for Deep Fascial Space Infections. J Oral Maxillofac Surg. 2021;79(10):e55–6 DOI: https://doi.org/10.1016/j.joms.2021.08.078
Qian Y, Ge Q, Zuo W, Cheng X, Xing D, Yang J, et al. Maxillofacial space infection experience and risk factors: a retrospective study of 222 cases. Ir J Med Sci. 2021;190(3):1045–53 DOI: https://doi.org/10.1007/s11845-020-02431-z
Bali RK, Sharma P, Gaba S, Kaur A, Ghanghas P. A review of complications of odontogenic infections. National journal of maxillofacial surgery. 2015 Jul;6(2):136 DOI: https://doi.org/10.4103/0975-5950.183867
Yonetsu K, Izumi M, Nakamura T. Deep facial infections of odontogenic origin: CT assessment of pathways of space involvement. Am J Neuroradiol. 1998;19(1):123–8
Sebastian A, Antony PG, Jose M, Babu A, Sebastian J, Kunnilathu A. Institutional microbial analysis of odontogenic infections and their empirical antibiotic sensitivity. Journal of oral biology and craniofacial research. 2019 Apr 1;9(2):133-8
Sebastian A, Antony PG, Jose M, Babu A, Sebastian J, Kunnilathu A. Institutional microbial analysis of odontogenic infections and their empirical antibiotic sensitivity. JOral Biol Craniofacial Res. 2019;9(2):133–8. microbial analysis of odontogenic infections and their empirical antibiotic sensitivity. J Oral Biol Craniofacial Res. 2019;9(2):133–8 DOI: https://doi.org/10.1016/j.jobcr.2019.02.003
Zhang C, Tang Y, Zheng M, Yang J, Zhu G, Zhou H, et al. Maxillofacial space infection experience in West China: A retrospective study of 212 cases. Int J Infect Dis. 2010;14(5):e414–7 DOI: https://doi.org/10.1016/j.ijid.2009.08.002
Yew CC, Ng MP, Ling XF, Tew MM. Orofacial infection and influencing factors on prolonged hospital stay: A four year retrospective study of 207 cases. J Oral Maxillofac Surgery, Med Pathol. 2021;33(1):7–12 DOI: https://doi.org/10.1016/j.ajoms.2020.06.007
Fu B, McGowan K, Sun H, Batstone M. Increasing use of intensive care unit for odontogenic infection over one decade: incidence and predictors. Journal of Oral and Maxillofacial Surgery. 2018 Nov 1;76(11):2340-7. DOI: https://doi.org/10.1016/j.joms.2018.05.021
Lao M, Li C, Li J, Chen D, Ding M, Gong Y Opportunistic invasive fungal disease in patients with type 2 diabetes mellitus from Southern China: Clinical features and associated factors. J Diabetes Investig. 2020;11(3):731–44 DOI: https://doi.org/10.1111/jdi.13183
Shar M khan, Ali S, Farooq MU, Sadiq H, Junaid MJ, Rana ZA. Relationship of Diabetes Mellitus Among The Patients Reporting With Facial Space Infection. Ann PIMS-Shaheed Zulfiqar Ali Bhutto Med Univ. 2022;18(3):148–52. DOI: https://doi.org/10.48036/apims.v18i3.640
Ko HH, Chien WC, Lin YH, Chung CH, Cheng SJ. Examining the correlation between diabetes and odontogenic infection: A nationwide, retrospective, matched-cohort study in Taiwan. PLoS One. 2017;12(6):e0178941 DOI: https://doi.org/10.1371/journal.pone.0178941
Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, et al. Clinical and bacteriological influence of diabetes mellitus on deep neck infection: Systematic review and meta-analysis. Head Neck. 2014;36(10):1536–46 DOI: https://doi.org/10.1002/hed.23776
James M, Varghese TP, Sharma R, Chand S. Association between metabolic syndrome and diabetes mellitus according to International Diabetic Federation and National Cholesterol Education Program Adult Treatment Panel III criteria: a Cross-sectional study. Journal of Diabetes & Metabolic Disorders. 2020 Jun;19:437-43 DOI: https://doi.org/10.1007/s40200-020-00523-2
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Annum Zamir Zamir, Sara Ali, Saima Khan, Yasir Rehman Khattak, Sheema, Anum Wajid, Jawad Ullah Khattak
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
