Bacterial Profile and Antimicrobial Susceptibility Pattern of Aerobic Vaginal Pathogens in Gynae Patients Visiting to Khyber Teaching Hospital Peshawar
DOI:
https://doi.org/10.37762/jgmds.8-4.258Keywords:
Aerobic Vaginal Pathogens, Aerobic Vaginitis, AntibiogramAbstract
OBJECTIVES:
The aim of this study was to determine the prevalent aerobic vaginal bacteria and their antibiogram to commonly prescribed antibiotics for the treatment of aerobic vaginitis (AV).
METHODOLOGY:
A total of 200 high vaginal swabs (HVS) samples were collected from different AV suspected patients visiting Khyber Teaching Hospital (KTH) and processed for identification of bacterial isolates followed by antibiotic susceptibility patterns as per CLSI protocols.
RESULTS:
Out of 200 clinical samples, 70 (35%) HVS isolates yielded bacterial growth. Of the isolates, E.coli was the common pathogen 36 (51.4%) followed by S.aureus 20 (28.5%), Enterobacter spp 08 (11.4%), Pseudomonas spp 04 (5.7%) and Citrobacter spp 02 (2.8%). The highest prevalence was observed in the age group of 21-35 years (31.4%) followed by age groups 16-20 years (25.7%) and 26-30 years. S.aureus isolates (n=20) were resistant to ciprofloxacin (90%), cephradine (70%), erythromycin (70%), gentamicin (50%) and cefotaxime (40%) while 1 (5%) of each isolate was resistant to methicillin and vancomycin. Majority of the gram-negative isolates (n=50) were resistant to cotrimoxazole, cephalosporins, quinolones, aminoglycosides and susceptible to carbapenems, tigecycline, sulbactam and tazobactam.
CONCLUSION:
Aerobic vaginitis should be treated very selectively in order not to kill the beneficial bacteria. Before treating AV, the causative agents should be accurately identified and tested for drug susceptibility patterns and empirical antibiotic therapy should be avoided.
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Copyright (c) 2021 Muhammad Asghar, Naheed ., Aakash Ahmad Khattak, Sadiq Azam, Noor Rehman, Ibrar Khan, Gul e Sehra, Anila Farid
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