Frequency to Non-Compliance to Oral Iron Therapy in Pregnancy and Common Factors Leading to it
DOI:
https://doi.org/10.37762/jgmds.9-1.175Keywords:
Non-compliance , Oral iron, Pregnancy, Gynecology, Neonate, MotherAbstract
OBJECTIVES:
The objective of this study was to determine frequency of non-compliance to oral iron therapy in pregnancy and common factors leading to it.
METHODOLOGY:
It was a cross-sectional study done in the Department of Obstetrics and Gynecology of Lady Willington Hospital Lahore, Pakistan. The duration of this study was six months i.e., 3rd October 2019 to 2nd March 2020. All antenatal patients between ages of 18 to 45 years presented in the obstetrics outdoors or admitted in the ward were included in this study. A total of 245 patients were included in this study by consecutive non-probability sampling. Patients with gynecological problems, patients dependent on others for their medication cost, patients with psychiatric illness or physical disability were excluded. Post stratification Chi-square test was applied keeping P-value ≤0.05 as significant
RESULTS:
Among 245 patients, mean age was 27±2.16 years. Iron supplement used by 245 patients was analyzed as 159 (65%) patients had used the iron supplement while 86 (35%) patients didn’t use iron supplements (P-value 0.001). Iron supplement used by 245 patients was analyzed and only 93 (38%) patients had used the iron supplement while 152 (62%) patients didn’t use iron supplements.
CONCLUSION:
The coverage of antenatal iron and folic acid supplements is very low in the surveyed districts of Pakistan due to lack of parental education and older aged women belonging to poor households.
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Abdulrehman J, Lausman A, Tang GH, Nisenbaum R, Petrucci J, Pavenski K, et al. Development and implementation of a quality improvement toolkit, iron deficiency in pregnancy with maternal iron optimization (IRON MOM): a before-and-after study. PLoS Med. 2019;16(8):e1002867 DOI: https://doi.org/10.1371/journal.pmed.1002867
Ajepe AA, Okunade KS, Sekumade AI, Daramola ES, Beke MO, Ijasan O, et al. Prevalence and foetomaternal effects of iron deficiency anaemia among pregnant women in Lagos, Nigeria. PLoS ONE. 2020;15(1):e0227965 DOI: https://doi.org/10.1371/journal.pone.0227965
Asadi N, Vafaei H, Kasraeian M, Yoosefi S, Faraji A, Abbasi L. Effects of prophylactic iron supplementation on outcome of nonanemic pregnant women: a non-randomized clinical trial. J Chin Med Assoc. 2019;82(11):840-4 DOI: https://doi.org/10.1097/JCMA.0000000000000184
Ba DM, Ssentongo P, Kjerulff KH, Na M, Liu G, Gao X, et al. Adherence to iron supplementation in 22 Sub-Saharan African countries and associated factors among pregnant women: a large population-based study. Curr Dev Nutr. 2019;3(12):nzz120 DOI: https://doi.org/10.1093/cdn/nzz120
Brannon PM, Taylor CL. Iron supplementation during pregnancy and infancy: uncertainties and implications for research and policy. Nutrients. 2017;9(12):1327 DOI: https://doi.org/10.3390/nu9121327
Habib MA, Raynes-Greenow C, Soofi SB, Ali N, Nausheen S, Ahmed I, et al. Prevalence and determinants of iron deficiency anemia among non-pregnant women of reproductive age in Pakistan. Asia Pac J Clin Nutr. 2018;27(1):195-203
Vázquez LI, Arija V, Aranda N, Aparicio E, Serrat N, Fargas F, et al. The effectiveness of different doses of iron supplementation and the prenatal determinants of maternal iron status in pregnant Spanish women: ECLIPSES study. Nutrients. 2019;11(10):2418 DOI: https://doi.org/10.3390/nu11102418
Inca-Caxi V, Munares-García O. Factors associated with adherence to iron supplements in pregnant women attended at a health center in Cañete, Peru. Int J Matern Fetal Health. 2020;5(1):3-10
Iqbal S, Ekmekcioglu C. Maternal and neonatal outcomes related to iron supplementation or iron status: a summary of meta-analyses. J Matern Fetal Neonat Med. 2019;32(9):1528-40 DOI: https://doi.org/10.1080/14767058.2017.1406915
Kessani L, Kumar R, Rathore A, Khalid R. Associated factors and compliance with iron-folic acid therapy among pregnant women of Karachi, Pakistan. Rawal Med J. 2018;43(2):319-23
Khan GN, Ariff S, Kureishy S, Sajid M, Rizvi A, Garzon C, et al. Effectiveness of wheat soya blend supplementation during pregnancy and lactation on pregnancy outcomes and nutritional status of their infants at 6 months of age in Thatta and Sujawal districts of Sindh, Pakistan: a cluster randomized-controlled trial. Eur J Nutr. 2021;60:781-9 DOI: https://doi.org/10.1007/s00394-020-02276-3
Larson LM, Phiri KS, Pasricha SR. Iron and cognitive development: what is the evidence?. Ann Nutr Metab. 2017;71(Suppl 3):25-38 DOI: https://doi.org/10.1159/000480742
Mahmood T, Rehman A, Tserenpil G, Siddiqui F, Ahmed M, Siraj F, et al. The association between iron-deficiency anemia and adverse pregnancy outcomes: a retrospective report from Pakistan. Cureus. 2019;11(10):e5854 DOI: https://doi.org/10.7759/cureus.5854
Milman N, Taylor CL, Merkel J, Brannon PM. Iron status in pregnant women and women of reproductive age in Europe. Am J Clin Nutr. 2017;106(Suppl_6):1655S-62S DOI: https://doi.org/10.3945/ajcn.117.156000
Miranda VI, Santos IS, Silveira MF, Silveira MP, Pizzol TD, Bertoldi AD. Validity of patient-reported anemia and therapeutic use of iron supplements during pregnancy: 2015 Pelotas (Brazil) birth cohort. Cad Saude Publica. 2018;34(6):e00125517
Okam MM, Koch TA, Tran M. Iron supplementation, response in iron-deficiency anemia: analysis of five trials. Am J Med. 2017;130(8):991.e1-e8 DOI: https://doi.org/10.1016/j.amjmed.2017.03.045
Parisi F, Berti C, Mandò C, Martinelli A, Mazzali C, Cetin I. Effects of different regimens of iron prophylaxis on maternal iron status and pregnancy outcome: a randomized control trial. J Matern Fetal Neonat Med. 2017;30(15):1787-92 DOI: https://doi.org/10.1080/14767058.2016.1224841
Symington EA, Baumgartner J, Malan L, Wise AJ, Ricci C, Zandberg L, et al. Maternal iron-deficiency is associated with premature birth and higher birth weight despite routine antenatal iron supplementation in an urban South African setting: the NuPED prospective study. PLoS ONE. 2019;14(9):e0221299 DOI: https://doi.org/10.1371/journal.pone.0221299
Tang L, Lee AH, Yau KK, Hui YV, Binns CW. Consumption of dietary supplements by Chinese women during pregnancy and postpartum: a prospective cohort study. Matern Child Nutr. 2017;13(4):e12435 DOI: https://doi.org/10.1111/mcn.12435
Thomas MS, Demirchyan A, Khachadourian V. How effective is iron supplementation during pregnancy and childhood in reducing anemia among 6–59 months old children in India?. Front Public Health. 2020;8:234 DOI: https://doi.org/10.3389/fpubh.2020.00234
Rashid H, Saleem S, Babar KM, Mahmood K, Younis H, Maheen S. Compliance of iron supplementation during pregnancy and factors effecting compliance. Prof Med J. 2019;26(12):2128-34 DOI: https://doi.org/10.29309/TPMJ/2019.26.12.3318
Wilson RL, Gummow JA, McAninch D, Bianco-Miotto T, Roberts CT. Vitamin and mineral supplementation in pregnancy: evidence to practice. J Pharm Pract Res. 2018;48(2):186-92 DOI: https://doi.org/10.1002/jppr.1438
Yang J, Kang Y, Cheng Y, Zeng L, Shen Y, Shi G, et al. Iron intake and iron status during pregnancy and risk of congenital heart defects: a case-control study. Int J Cardiol. 2020;301:74-9 DOI: https://doi.org/10.1016/j.ijcard.2019.11.115
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