
7
J Gandhara Med Dent Sci
July - September 2026
Notably, the current ndings cannot be used to
generalize conclusions about the superiority of SMD
across all outcomes; the most convincing data in this
dataset pertain to reduced pain scores and enhanced
tissue healing at 3 months.
LIMITATIONS
The current research has several limitations. To start
with, the non-randomized design and lack of allocation
concealment limit internal validity and create potential
selection bias. Despite the comparability testing at
baseline not showing statistically signicant dierences
among groups, residual confounding was not corrected,
and multivariable adjustment was not performed due to
the small sample size. Second, the sample size in this
case was relatively small and selected from a single
center, which minimizes statistical power and limits
generalizability. Third, a three-month follow-up was
not long enough to evaluate long-term outcomes such
as recurrent turbinate hypertrophy, sustained symptom
relief, synechiae, or late crusting. Fourth, VAS, nasal
obstruction grading, and Lund and Kennedy grading
were found to be clinically useful, but some outcomes
were partially subjective; it was not possible to blind
the assessor, and inter-rater reliability was not
evaluated. Fifth, they did not include patient
satisfaction, disease-specic quality of life, or validated
scales of nasal symptoms, such as the NOSE scale or
SNOT-22. It is advised that multicenter randomized
controlled trials include allocation concealment, blinded
outcome assessment where possible, increased sample
sizes, validated patient-reported outcome measures, and
extended follow-up duration.
CONCLUSIONS
In this study, SMD was associated with less pain and
enhanced tissue healing at 3 months after the operation
compared to PIT. The outcomes of nasal obstruction,
crusting, and hemorrhage showed a numerical
advantage for SMD, although the results were not
considered statistically signicant. Therefore, SMD
may be considered a safe and helpful option to manage
inferior turbinate hyperplasia, but the results should be
interpreted with caution, as it is a non-randomized
study of smaller size or lacks sucient follow-up.
CONFLICT OF INTEREST: None
FUNDING SOURCES: None
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