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J Gandhara Med Dent Sci
ORIGINAL ARTICLE
July - September 2026
How to cite this article
COMPARISON OF OUTCOMES OF PARTIAL TURBINECTOMY VERSUS MUCOSAL DIATHERMY
IN PATIENTS WITH INFERIOR TURBINATE HYPERTROPHY
Aqsa Yaqub Muhammad Zeeshan Ashraf
1
,
1
, Sarfraz Latif
2
, Rabia Aftab
1
, Muhammad Israr
1
, Zia Us Salam
3
Ashraf MZ, Yaqub A, Latif S, Aftab
R, Israr M, Salam ZU. Comparison o
f
Outcomes of Partial Turbinectomy
Versus Mucosal Diathermy in Patients
with Inferior Turbinate Hypertrophy. J
Gandhara Med Dent Sci.
2026;13(3):03-08.
Date of Submission: 15-01-2026
Date Revised: 04-06-2026
Date Acceptance: 18-06-2026
2
Associate Professor, Department of
ENT, Shaikh Zayed Hospital, Lahore
3
Consultant, Department of ENT, Shaikh
Zayed Hospital, Lahore
Correspondence
1
Muhammad Zeeshan Ashraf,
Postgraduate Resident, Department of
ENT, Shaikh Zayed Hospital, Lahore
:
:
+92-348-6504550
zeeshansmdc@gmail.com
ABSTRACT
OBJECTIVES
To compare the outcomes of partial turbinectomy versus mucosal diathermy
in patients with inferior turbinate hypertrophy.
METHODOLOGY
The ENT Department at Sheik Zayed Hospital, Lahore, conducted this
single-center, non -randomized, controlled study. Sixty adults aged 18-60
years with clinically and radiologically conrmed inferior turbinate
hypertrophy were selected and sequentially assigned to two equal groups
upon screening and informed consent. Group A had partial inferior
turbinectomy (PIT), whereas Group B had submucosal diathermy (SMD).
Comparison of the groups with the baselines was conducted. Variability in
operators was minimized using a standardized operative protocol. The pain
after the operation was measured using a 10-point Visual Analog Scale
(VAS), nasal obstruction was measured on a 0-3 scale, nasal crusting was
graded using the Lund and Kennedy system, and endoscopic assessment
assessed tissue healing. The three-month follow-up was made.
RESULTS
There was similarity between groups in baseline demographic and clinical
variables. Mean postoperative pain was signicantly lower in the SMD g roup
than in the PIT group on day 1 (mean dierence 2.67; 95% CI 2.14-3.20;
Cohen's d=2.61; p=0.0001) and at one month (mean dierence 1.83; 95% CI
1.43-2.23; Cohen's d=2.36; p=0.0001). Nasal obstruction, crusting, and
bleeding outcomes in the nasal passages were numerically predisposed to
SMD, although a majority of between-group comparisons were non-
signicant. The SMD group exhibited a statistically signicantly higher
(0.003) good tissue healing at three months (76.67%) compared with the PIT
group (33.33%).
CONCLUSION
SMD, in this non-randomized study, was associated with less postoperative
pain and faster tissue healing at 3 months compared to PIT. Other clinical
outcomes showed positive trends in SMD but should be used with caution due
to small sample sizes, non-random subject allocation, and limited follow-up..
KEYWORDS: Submucosal Diathermy, Partial Turbinectomy, Nasal
Obstruction
effectiveness often diminishes with long-term use.
Surgery aims to reduce the bulk of the inferior
turbinates, enhance nasal patency, and preserve
physiological nasal function.
2
To achieve signicant
patient outcomes, surgical treatment options have been
devised to address the symptoms of turbinate
hypertrophy. Examples of traditional methods of
surgery include partial inferior turbinectomy (PIT),
submucosal diathermy (SMD), electrocautery, laser
cautery, cryosurgery, and radiofrequency ablation.
Turbinectomy oers instant relief by removing
hypertrophic tissue, but its mainstream acceptability is
restricted by the hazards involved, including bleeding,
crust development, synechiae, and postoperative pain.
4,5
As a result, minimally invasive methods like
submucosal diathermy have drawn interest since they
INTRODUCTION
The hypertrophy of the inferior turbinate is a major
cause of nasal airow obstruction, leading to persistent
nasal congestion and reduced quality of life. It usually
results from chronic inammatory disorders, such as
allergic rhinitis and vasomotor rhinitis, or secondary
compensatory hypertrophy due to septal deviation, and
is regularly seen in otolaryngology clinical practice.
1
Mucosal thickening and submucosal brosis are
common symptoms of chronic inammatory
alterations, which eventually result in persistent nasal
blockage that is resistant to medical intervention.
Examples of conservative treatment options include
intranasal corticosteroids, antihistamines,
decongestants, and immunotherapy; however, their
https://doi.org/10.37762/jgmds.13-3.852
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J Gandhara Med Dent Sci
July - September 2026
can successfully lower turbinate volume while causing
the least amount of tissue damage. High-frequency
electrical currents are used in submucosal diathermy to
produce controlled submucosal thermal injury and
consequent brosis, resulting in a long-term decrease in
turbinate size. Notwithstanding its widespread use,
submucosal diathermy has been linked to postoperative
side eects, including crusting, nasal dryness, adhesion
formation, and sporadic hypertrophy recurrence. As a
result, physicians are looking into alternative surgical
methods that may yield better results.
6,7,8
There is still a
conspicuous lack of clear evidence to guide clinicians
over the best surgical method between submucosal
diathermy and partial inferior turbinectomy, despite the
abundance of research. The conicting ndings of
previous studies on both the immediate safety and long-
term eectiveness of the treatment make it critically
important to conduct more comparative studies. The
current study aims to bridge this gap by systematically
assessing clinical outcomes, complication rates, and the
sustainability of symptom relief following these two
common surgical procedures. This research should lead
to better patient outcomes in the treatment of inferior
turbinate hypertrophy, provide valuable clinical
guidance, and support evidence-based therapeutic
decision-making.
METHODOLOGY
This is a single-center, non-randomized controlled
study conducted in the ENT Department at Sheik Zayed
Hospital, Lahore, between September 2025 and
December 2025, with the consent of the institutional
ethical review committee. The research was structured
as a pragmatic comparison since the practice of both
interventions was common in the department.
Randomization and allocation concealment were not
performed. Eligible patients were sequentially assigned
to two equal treatment groups after eligibility screening
and written informed consent, based on the intended
surgical procedure in routine departmental practice; this
pragmatic allocation approach was used because both
procedures were already routinely performed in the
unit. It has been recognized that this allocation method
could introduce selection bias and, therefore, limit
internal validity. Given a condence level of 95 and a
power of 80, assuming that the percentage of excellent
healing would be 60 percent with PIT and 84 percent
with SMD, with 30 patients in each group, patients aged
18-60 years old with inferior turbinate hypertrophy
(enlargement of the inferior turbinate to produce a
clinically signicant nasal obstruction) were the
participants. Clinical evaluation and diagnostic nasal
endoscopy, performed by a consultant ENT specialist,
were used to make the diagnosis. When the inferior
cavity, hypertrophy was deemed clinically signicant,
which is grade 2 (moderate hypertrophy, 50-75 percent
of the nasal cavity) or grade 3 (severe hypertrophy, > 75
percent of the nasal cavity or touching the nasal
septum). Radiological conrmation Computed
tomography (CT) of the coronal, axial, and sagittal
sections of the scan, with a slice thickness of 2 mm and
a maximum diameter of the turbinate, was used to
obtain radiological conrmation. Other inclusion
criteria included persistent nasal obstruction for over six
months and an ineective response to at least three
months of conservative medical treatment, including
intranasal corticosteroids and antihistamines. Patients
who had nasal obstruction that had been treated with
nasal polyps, septal deviation, sinuitis or any other
major sinonasal disease; uncontrolled allergic rhinitis or
ongoing immunotherapy; previous nasal or turbinate
surgery; defective state of the nasal mucosa, including
Wegener granulomatosis, sarcoidosis, or cystic brosis;
bleeding disorders or anticoagulant therapy; inability to
comply with the study protocol; and cognitive
impairment to hinder understanding and compliance
were excluded. All participants had written informed
consent. Age at baseline, sex, symptom duration,
preoperative grade of hypertrophy of the turbinate, and
preoperative grade of nasal obstruction were measured
prior to surgery to compare the groups. They were all
carried out in accordance with a prescribed
departmental protocol, under the direct supervision of
the same senior ENT consultant, to minimize operator
variability. All surgeries were performed by means of
oral intubation and general anesthesia. Premedication -
Cotton pledgets moistened with noradrenaline
(1:200000) were placed in each nasal canal for about 5
minutes to reduce bleeding and enhance visibility.
Group A: Partial Inferior Turbinectomy (PIT): The
inferior turbinate was seen with an endoscope or nasal
speculum following just sucient decongestion and
anesthesia. The scissors were turbinectomy scissors
used to excise the medial one-third of the superior
hypertrophied inferior turbinate, including the mucosal
and bony portions. Only the anterior two-thirds of the
turbinate was resected to avoid leaving the posterior
turbinate and to minimize the possible loss of too much
tissue. Bleeding points were managed with caution of
bipolar or nasal packing, when necessary. Group B:
Submucosal Diathermy (SMD): The inferior turbinate
was exposed, then an insulated diathermy needle was
inserted into the submucosal space at the anterior of the
turbinate and moved parallel to the bone. A low volume
of coagulation current was used, with a 70-watt low-
voltage current applied as the needle was gradually
drawn out. The superior, middle, and inferior portions
of the turbinate were covered by two to three passes
until there was blanching and visible shrinkage of the
turbinate occupied 50 percent or more of the nasal
Comparison of Outcomes of Partial Turbinectomy Versus Mucosal Diathermy
5
J Gandhara Med Dent Sci
July - September 2026
mucosa. The mucosal surface was maintained as much
as possible, and submucosal thermal injury was
restricted to induce brosis and reduce the volume.
Before the procedure was completed, Hemostasis was
achieved. In both groups, the bilateral nostrils were
packed with ribbon gauze immersed in antibiotics
overnight. Patients were given systemic decongestants,
antibiotics, and analgesics as per the departmental
postoperative protocol, and packing was done after 48
hours. Patients were advised not to blow their noses or
manipulate them. To enhance comfort and promote
mucosal healing, nasal saline irrigation was
recommended 1 month after the pack was removed.
Postoperative treatment involved the use of systemic
decongestants, antibiotics, and painkillers. Patients
were advised not to rub their noses or blow them. Nasal
saline irrigation was advised to be performed over one
month after nasal packs were removed at 48 hours to
facilitate healing and comfort. Each problem was
risk dierences or Cramér's V (categorical outcomes).
A p-value less than 0.05 was taken as statistically
significant.
addressed in accordance with the accepted guidelines.
Predened criteria and predetermined intervals were
used to evaluate outcomes. On the rst day of the
postoperative period and at one-month follow-up, a 10-
point Visual Analog Scale (VAS), a commo n patient-
reported pain scale, was used to measure postoperative
nasal pain. The patients were graded on a structured
ordinal scale (0-3) to assess nasal obstruction before
surgery and at 1 and 3 months after surgery. At two
weeks and three months, endoscopy was used to
measure nasal crusting by the standardized Lund and
Kennedy system. At 3 months, diagnostic nasal
endoscopy and the Lund and Kennedy indices were
used to assess tissue healing. Direct inspection of nasal
packing and clinical records categorized bleeding
within 48 hours of surgery as minimal, moderate, or
severe. Due to the apparent postoperative appearance
depending on the procedure, formal blinding of the
assessor was not feasible, but prespecied scales were
to be used to minimize observer bias. There was no
inter-rater reliability. The data analysis was conducted
with SPSS version 26.0. Descriptive statistics have been
used to summarize demographic and baseline clinical
data, including age, gender, duration of nasal
obstruction symptoms, preoperative turbinate grade,
and preoperative nasal obstruction grade, and to
compare them across groups to determine baseline
comparability. Categorical data (postoperative nasal
obstruction grade, nasal crusting grade, severity of
bleeding, and Tissue healing grade) were represented
by frequencies and percentages. Mean +/standard
deviation was used to display continuous data, such as
pain VAS values. Chi-square test and independent
samples t-test were used. Besides p-values, which are
also presented where necessary, are condence
intervals, such as 95% condence intervals for mean
dierences and Cohen d (continuous outcomes), and
RESULTS
Table 1: Distribution of Dierent Variables (n=60)
Number (%)
Age (years)
18-40
41-60
Gender
Male
Female
Duration of symp
toms (months)
≤12
>12
Grading of
Inferior
T urbinate
Hypertrophy
01
02
03
04
Nasal
obstruction
grade
00
01
02
03
16
(53.33%)
14
(46.67%)
18
(60.0%)
12
(40.0%)
11
(36.67%)
19
(63.33%)
03
(10.0%)
07
(23.33%)
12
(40.0%)
08
(26.67%)
00
(0.0%)
06
(20.0%)
08
(26.67%)
16
(53.33%)
15
(50.0%)
15
(50.0%)
19
(63.33%)
11
(36.67%)
12
(40.0%)
18
(60.0%)
02
(6.67%)
09
(30.0%)
11
(36.67%)
08
(26.67%)
01
(3.33%)
07
(23.33%)
09
(30.0%)
13
(43.33%)
Group A(n=30) Group B (n=30)
Table 2: Comparison of VAS Score
V AS
score
Group A (n=30) Group B (n=30) P-Value
Mean ± SD Mean ± SD
Day 1
4.87 ± 1.14 2.20 ± 0.89 0.0001
1 month
2.90 ± 0.78 1.07 ± 0.77 0.0001
Table 3: Comparison of Outcome at 2 Weeks.
(n=30)
P-
V alue
00 07
(23.33%)
14
(46.67%)
0.299
01 09
(30.0%)
07
(23.33%)
02 08
(26.67%)
05
(16.67%)
03 06
(20.0%)
04
(13.33%)
Nasal
obstruction
grade
Nasal
crusting
grade
00 13
(43.33%)
19
(63.33%)
0.298
01 09
(30.0%)
06
(20.0%)
02 08
(26.67%)
05
(16.67%)
Hemorrhage
severity
Minimal 14
(46.67%)
21
(70.0%)
0.167
Moderate 11
(36.67%)
07
(23.33%)
Severe 05
(16.67%)
02
(6.67%)
Tissue
Healing
Poor 15
(50.0%)
08
(26.67%)
0.087
Moderate 07
(23.33%)
06
(20.0%)
Good 08
(26.67%)
16
(53.33%)
Group A Group B
Comparison of Outcomes of Partial Turbinectomy Versus Mucosal Diathermy
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J Gandhara Med Dent Sci
July - September 2026
Table 4: Comparison of Outcomes at 3 Months
P
-
value
Nasal
obstruction
grade
00 20
(66.67%)
25
(83.33%)
0.394
01 04
(13.33%)
03 (10.0%)
02 05
(16.67%)
02
(6.67%)
03 01
(3.33%)
00 (0.0%)
Nasal
crusting
grade
00 19
(63.33%)
23
(76.67%)
0.385
01
10
(33.33%)
07 (23.33%)
02 01
(3.33%)
00 (0.0%)
Hemorrhage
severity
Minimal 22
(73.33%)
26 (86.67%)
0.341
Moderate 07
(23.33%)
04
(13.33%)
Severe 01
(3.33%)
00 (0.0%)
Tissue
Healing
Poor 06
(30.0%)
02
(6.67%)
0.003
Moderate 14
(46.67%)
05 (16.67%)
Good 10
(33.33%)
23
(76.67%)
(n=30)
Group A Group B
DISCUSSION
One of the most frequent reasons patients come to the
ENT OPD is nasal blockage. One of the most common
causes of nasal blockage is hypertrophy of the inferior
turbinates, which can be caused by allergic or
vasomotor rhinitis. Although a wide range of treatment
options are available, the comparative benets of the
various treatments are highly disputed.
10,11,12
In the
present study, the mean age was 46.90/+ 7.86 years.
The average age of the patients in groups A and B was
46.07 ± 7.92 and 46.73 ± 8.61 years, respectively. The
mean age of the groups did not dier signicantly
(p>0.05). The study mean of the groups that have
undergone partial inferior turbinectomy and
submucosal diathermy was 28.35 + 8.12 and 30.93 +
7.72 years respectively, as explained by Saleem et al.
In
a dierent study, Nawaz et al. found that PIT group had
a mean age of 26.5 years, whereas SMD group had a
mean age of 27.2 years.
13,14
Males predominated in both
groups in this study (60.0% in the PIT group and
63.33% in the SMD group). Similarly, group B (partial
inferior turbinectomy group) had 67.5% men, and
group A (submucosal diathermy group) had 72.5%
males, according to Nawaz et al. Of the 60 patients
enrolled in the trial, 20 (66.7%) were male and 10
(33.3%) were female in Group B (PIT), while 12
(40.0%) were male and 18 (60.0%) were female in
Group A (SMD), according to Vishnu and
Rajamma.
14,15
Nasal blockage decreased signicantly in
both treatment groups, but in the current study, the
dierences in nasal obstruction grade between the two
groups at 2 weeks and 3 months were not signicant.
Even though the percentage of patients who were
completely relieved of obstruction was greater in the
SMD group at the two follow-ups, the condence
intervals are wide, indicating that the extent of benet
is not certain. Thus, the ndings need to be viewed as a
positive outcome for SMD rather than as conclusive
short-term obstruction relief. Gomaa et al. also reported
no statistically signicant dierence in the eect of
nasal obstruction between PIT and SMD at early
follow-up, but Saleem et al. and Nawaz et al. reported
better short-term outcomes of obstruction on
turbinectomy.
9,13,14
Conversely, Gangararaj et al. found
the initial relief with SMD but overall reversals with
PIT at six months.
16
These variations can include
dierences in surgical procedure, initial severity,
follow-up period, grading of outcomes, and sample
size. In the current study, there was a signicant
reduction in postoperative pain after SMD, and eect
sizes were large at both day 1 and one-month follow-
up. The discovery is biologically plausible, as SMD
preserves the surface mucosa and causes controlled
submucosal damage, and PIT destroys mucosa and
bony tissue, which may lead to increased raw surface
area, inammation, and postoperative pain. Vishnu and
Rajamma and Gangaraj et al. have reported similar
patterns of diminished pain in the aftermath of SMD;
however, studies published on the topic have found a
mixed pattern of pain depending on the situation of
tissue removal, cautery settings, analgesic practices,
and timing.
15,16
All these could justify the disparity
between the current results and those that found a less
pronounced pain dierence in their studies. In this
study, bleeding severity was numerically greater in PIT
cases than in SMD cases, but the dierence was
statistically insignicant. It is comparable to the
mechanism of PIT, where direct excision of tissue
exposes vascular surfaces, whereas SMD can be applied
by accomplishing volume reduction via submucosal
mucosal coagulation, which preserves the mucosal
integrity. Vishnu and Rajamma obtained similar results,
as did Imad et al., Al-Baldawi, and Gangaraj et al., who
reported increased rates of bleeding following
PIT.
15,16,18,19
However, the given sample size of only 30
patients per group may have been underpowered to
detect moderate dierences in bleeding severity. Three
months showed tissue healing was better in the SMD
group, and crusting favored SMD numerically but was
not signicant. The mucosal surface could clarify the
advancement of healing following SMD and the
minimized raw area postoperatively. Conversely, PIT
can cause an immediate decrease in turbinate volume
but may be associated with increased mucosal injury,
crust formation, and a slower recovery of epithelial
cells. Inconclusive eects have been reported in
previous research, with some showing lower crusting
following SMD and others showing no signicant
dierences in the long term.
9,15,16
The variability in the
results among the research could be attributed to the
differences in postoperative campaigns in using the
nasal toilet, saline irrigation adherence, cauterization
settings, and the time of the endoscopic follow-up.
Comparison of Outcomes of Partial Turbinectomy Versus Mucosal Diathermy
7
J Gandhara Med Dent Sci
July - September 2026
Notably, the current ndings cannot be used to
generalize conclusions about the superiority of SMD
across all outcomes; the most convincing data in this
dataset pertain to reduced pain scores and enhanced
tissue healing at 3 months.
LIMITATIONS
The current research has several limitations. To start
with, the non-randomized design and lack of allocation
concealment limit internal validity and create potential
selection bias. Despite the comparability testing at
baseline not showing statistically signicant dierences
among groups, residual confounding was not corrected,
and multivariable adjustment was not performed due to
the small sample size. Second, the sample size in this
case was relatively small and selected from a single
center, which minimizes statistical power and limits
generalizability. Third, a three-month follow-up was
not long enough to evaluate long-term outcomes such
as recurrent turbinate hypertrophy, sustained symptom
relief, synechiae, or late crusting. Fourth, VAS, nasal
obstruction grading, and Lund and Kennedy grading
were found to be clinically useful, but some outcomes
were partially subjective; it was not possible to blind
the assessor, and inter-rater reliability was not
evaluated. Fifth, they did not include patient
satisfaction, disease-specic quality of life, or validated
scales of nasal symptoms, such as the NOSE scale or
SNOT-22. It is advised that multicenter randomized
controlled trials include allocation concealment, blinded
outcome assessment where possible, increased sample
sizes, validated patient-reported outcome measures, and
extended follow-up duration.
CONCLUSIONS
In this study, SMD was associated with less pain and
enhanced tissue healing at 3 months after the operation
compared to PIT. The outcomes of nasal obstruction,
crusting, and hemorrhage showed a numerical
advantage for SMD, although the results were not
considered statistically signicant. Therefore, SMD
may be considered a safe and helpful option to manage
inferior turbinate hyperplasia, but the results should be
interpreted with caution, as it is a non-randomized
study of smaller size or lacks sucient follow-up.
CONFLICT OF INTEREST: None
FUNDING SOURCES: None
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July - September 2026
AUTHORS CONTRIBUTION
The authors accept responsibility for all aspects of the work
and will ensure that any concerns regarding the accuracy or
integrity of any part are properly investigated and resolved.
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Muhammad Zeeshan Ashraf
-
Concept &
Design; Data
Acquisition; Data Analysis/Interpretation; Drafting
Manuscript;
Critical Revision;
Final Approval
Aqsa Yaqub
-
Concept & Design; Data Acquisition; Data
Analysis/Interpretation; Drafting Manuscript; Critical
Revision; Final Approval
Sarfraz Latif -
Concept & Design; Data Acquisition; Data
Analysis/Interpretation; Critical Revision;
Supervision;
Final
Approval
Rabia Aftab
-
Concept & Design; Data Acquisition; Data
Analysis/Interpretation; Critical Revision; Final Approval
Muhammad Israr
-
Concept & Design; Data Acquisition; Data
Analysis/Interpretation; Critical Revision; Final Approval
Zia Us Salam -
Concept & Design; Data Acquisition; Data
Analysis/Interpretation; Supervision; Final Approval
Comparison of Outcomes of Partial Turbinectomy Versus Mucosal Diathermy
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